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1090 A review of cervical cancer diagnosed in women over the age of 65
  1. S Baron and
  2. S Kaushik
  1. University Hospitals Sussex NHS Foundation Trust, Gynaecological Oncology, brighton, UK


Objectives To explore the incidence of cervix cancer following cessation of the UK cervical screening programme and compare this with the current UK screening programme guidelines.

Methodology 179 cases of cervical cancer diagnosed between 2016 and 2020 at University Hospitals Sussex were retrospectively reviewed. The screening history, grade, histology and stage of cancer were recorded.

Result(s)*Over a five-year period, 80 cases of cervical cancer were identified as being within the screened population. Of these 59 (74%) were under 65 years and 21 (26%) were over 65 years of age. An initial peak incidence was seen at 30-35 year age range, declining with further screening. Following cessation of screening, a secondary peak at 80-85 years was noted.

Of those diagnosed during screening (59.3%) were FIGO IA1 to IB2, however, only 9.5% of the over 65s were early stage. Similarly, 32.2% of those within screening age presented with a grade 1 cancer, with only 4.8% over 65 years being low grade. Histology in the under 65s revealed 44.1% were squamous cell carcinoma and 45.8% were HPV-related adenocarcinoma. In the over 65s this was 76.2% and 14.3% respectively.

Conclusion*Despite adherence to the screening programme, 25% of cervix cancer was diagnosed beyond screening age, approximately 16 years later. These patients were of more advanced stage and higher grade.

This preliminary exploration informs the need for a wider review of cervix cancer after the age of 65 and consideration of extension of the age of screening.

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