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EP995 Ultrasound patterns compared to histopathological findings in ovarian granulosa cell tumor
  1. C Prasciolu,
  2. C Del Pezzo,
  3. L Mereu and
  4. S Tateo
  1. Ospedale Santa Chiara, Trento, Italy


Introduction/Background Granulosa cell tumor (GCT) is the most common sex cord stromal tumor and constitute less than 5% of all ovarian cancers. Pre operative diagnosis is challenging. Sonographic findings are multiple, the mass could present with different patterns.

Methodology A retrospective study of histopathologically confirmed ovarian granulosa cell tumor that underwent preoperative ultrasound examination according to IOTA classification. Sonographic findings were compared with histopathological findings

Results A total of 11 patient with confirmed GCT were identified. The median age of patients was 55 years old. Ultrasound patterns were described using IOTA pattern. Almost all the tumors (90%) contained a solid component. Three (30%) were multilocular-solid, six (60%) were solid and one was multilocular. Five of the six solid masses didn’t show an omogeneous solid tissue but a large number of small locules or irregular shaped locules with solid tissue around, the only pure solid tumor was seen in the recurrence. Macroscopic appearance was similar to ultrasound description, most of the tumors (60%) were composed by solid and cystic areas in variable proportions. Two (20%) of the tumors were totally composed by cystic lesions. One macroscopic description was not availabile. The subjective assessment of the sonologist correctly suggested the specific diagnosis of GCT in three cases (30%). In three cases (30%) the sonologist impression was non conclusive, in three cases the diagnosis was malignant tumor; two (20%) were described as benign tumor.

Conclusion A correlation between sonographic findings based on IOTA classification of ovarian masses and pathologic findings was reported, but in 20% of cases the ultrasound scan can underestimate the diagnosis.

Disclosure Nothing to disclose.

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