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Oral Progesterone Treatment in a Young Woman With Müllerian Adenosarcoma Whose Ovary Was Preserved: A Case Report
  1. Sung Jong Lee, MD, PhD*,
  2. Jeong-Hoon Bae, MD, PhD*,
  3. Dong Chul Kim, MD,
  4. Jong Sup Park, MD, PhD* and
  5. Sung Eun Namkoong, MD, PhD*
  1. *Departments of Obstetrics and Gynecology, and
  2. Departments of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
  1. Address correspondence and reprint requests to Sung Eun Namkoong, Department of Obstetrics and Gynecology, College of Medicine, Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-040, South Korea. E-mail: nkse{at}


Müllerian adenosarcoma is a rare biphasic tumor in young women. These tumors can recur even after complete resection. We present a patient treated with oral progesterone after hysterectomy with ovary conservation. A 35-year-old woman had a diagnosis of adenosarcoma on hysteroscopic resection, which was estrogen and progesterone receptor positive. She underwent total hysterectomy with ovary conservation and has received oral medroxyprogesterone acetate treatment. At 15 months after surgery, there has been no disease recurrence. Oral medroxyprogesterone acetate therapy can be used effectively in young women with müllerian adenosarcoma whose ovaries are preserved.

  • Müllerian adenosarcoma
  • Conservative therapy
  • Oral progesterone

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