Clinical Trial

TRAINING-Ovary 01 (connecTed pRehabiliAtIoN pelvIc caNcer surGery): multicenter randomized study comparing neoadjuvant chemotherapy for patients managed for ovarian cancer with or without a connected pre-habilitation program

Eric Lambaudie, Cécile Bannier/Braticevic, Charlène Villaron/Goetgheluck, Christophe Zemmour, Jean-Marie Boher, Patrick Ben Soussan, Jihane Pakradouni, Clement Brun, Leonor Lopez Almeida, Patricia Marino

10.1136/ijgc-2020-002128

December 1, 2020

ICON 9—an international phase III randomized study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemotherapy

Osnat Elyashiv, Jonathan Ledermann, Gita Parmar, Laura Farrelly, Nicholas Counsell, Amanda Feeney, Fatima El-Khouly, Ian Macdonald, Andreia Neto, Esther Arthur-Darkwa, Eva Burnett, Gordon C Jayson, Linda Mileshkin, Charlie Gourley, Shibani Nicum

10.1136/ijgc-2020-002073

October 23, 2020

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

Anne Sophie V M van den Heerik, Nanda Horeweg, Remi A Nout, Ludy C H W Lutgens, Elzbieta M van der Steen-Banasik, G Henrike Westerveld, Hetty A van den Berg, Annerie Slot, Friederike L A Koppe, Stefan Kommoss, Jan Willem M Mens, Marlies E Nowee, Stefan Bijmolt, David Cibula, Tanja C Stam, Ina M Jurgenliemk-Schulz, An Snyers, Moritz Hamann, Aleida G Zwanenburg, Veronique L M A Coen, Katrien Vandecasteele, Charles Gillham, Cyrus Chargari, Karen W Verhoeven-Adema, Hein Putter, Wilbert B van den Hout, Bastiaan G Wortman, Hans W Nijman, Tjalling Bosse, Carien L Creutzberg

10.1136/ijgc-2020-001929

October 12, 2020

Sentinel lymph node biopsy versus pelvic lymphadenectomy in early-stage cervical cancer: a multi-center randomized trial (PHENIX/CSEM 010)

Hua Tu, He Huang, Bingna Xian, Jibin Li, Ping Wang, Weidong Zhao, Xiaojun Chen, Xing Xie, Chunyan Wang, Beihua Kong, Jing Xiao, Ping Zhang, Jihong Liu

10.1136/ijgc-2020-001857

September 24, 2020

Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal (PROTECTOR): protocol for a prospective non-randomised multi-center trial

Faiza Gaba, Sadiyah Robbani, Naveena Singh, W Glenn McCluggage, Nafisa Wilkinson, Raji Ganesan, Gareth Bryson, Gareth Rowlands, Charlotte Tyson, Rupali Arora, Ertan Saridogan, Helen Hanson, Matthew Burnell, Rosa Legood, D Gareth Evans, Usha Menon, Ranjit Manchanda, on behalf of the PROTECTOR team, Katie Snape, Sadaf Ghaem-Maghami, Gautam Mehra, Angela Brady, Adam Rosenthal, Michelle MacKintosh, Ian Harley, Sudha Sundar, Claire Newton, Omer Devaja, Tim Duncan, Supratik Chattopadhyay, Natalia Povolotskaya, Rema Iyer, Lucy Side, Anil Tailor, Manon van Seters, Suma Kodiathodi, Partha Sengupta, Iain Cameron, Sonali Kaushik, Karin Williamson, Katherine Edey, Sian Taylor, Andrew Phillips, Mark Willett, Tony Chalhoub, Sanjay Rao, Nicholas Matthews, Aarti Sharma, Scott Fegan, Mahalakshmi Gurumurthy, Kalpana Ragupathy, Beena Abdul, Ibraheem Hamoodi, Claire Park, Jane Borley, Richard Hutson, Kerryn Lutchman-Singh, Richard Peevor

10.1136/ijgc-2020-001541

September 8, 2020

Diagnostic performance of ultrasound in assessing the extension of the disease in patients with suspicion of malignant ovarian tumor: correlation between ultrasound parameters and Fagotti’s score

Maria Cristina Moruzzi, Giulia Bolomini, Francesca Moro, Floriana Mascilini, Silvia Ficarelli, Giuliana Beneduce, Maria Teresa Giudice, Tina Pasciuto, Rossana Moroni, Giovanni Scambia, Anna Fagotti, Antonia Carla Testa

10.1136/ijgc-2020-001606

September 7, 2020

DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment

Michelle McMullen, Katherine Karakasis, Bienvenu Loembe, Emma Dean, Graem Parr, Amit M Oza

10.1136/ijgc-2020-001694

September 2, 2020

A prospective multicenter international single-arm observational study on the oncological safety of the sentinel lymph node algorithm in stage I intermediate-risk endometrial cancer (SELECT, SEntinel Lymph node Endometrial Cancer Trial)

Tommaso Grassi, Andrea Mariani, David Cibula, Pamela T Soliman, Vera J Suman, Amy L Weaver, Silvana Pedra Nobre, Britta Weigelt, Gretchen E Glaser, Serena Cappuccio, Nadeem R Abu-Rustum

10.1136/ijgc-2020-001698

July 22, 2020

Laparoscopic cytoreduction After Neoadjuvant ChEmotherapy (LANCE)

Roni Nitecki, Jose Alejandro Rauh-Hain, Alexander Melamed, Giovanni Scambia, Rene Pareja, Robert L Coleman, Pedro T Ramirez, Anna Fagotti

10.1136/ijgc-2020-001584

July 20, 2020

Atezolizumab in combination with bevacizumab and chemotherapy versus bevacizumab and chemotherapy in recurrent ovarian cancer – a randomized phase III trial (AGO-OVAR 2.29/ENGOT-ov34)

Philipp Harter, Patricia Pautier, Els Van Nieuwenhuysen, Alexander Reuss, Andres Redondo, Kristina Lindemann, Christian Kurzeder, Edgar Petru, Florian Heitz, Jalid Sehouli, Nikolaus Degregorio, Pauline Wimberger, Alexander Burges, Nadin Cron, Jonathan Ledermann, Domenica Lorusso, Xavier Paoletti, Frederik Marme

10.1136/ijgc-2020-001572

June 30, 2020