Clinical Trial

ICON 9—an international phase III randomized study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemotherapy

Osnat Elyashiv, Jonathan Ledermann, Gita Parmar, Laura Farrelly, Nicholas Counsell, Amanda Feeney, Fatima El-Khouly, Ian Macdonald, Andreia Neto, Esther Arthur-Darkwa, Eva Burnett, Gordon C Jayson, Linda Mileshkin, Charlie Gourley, Shibani Nicum

10.1136/ijgc-2020-002073

October 23, 2020

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

Anne Sophie V M van den Heerik, Nanda Horeweg, Remi A Nout, Ludy C H W Lutgens, Elzbieta M van der Steen-Banasik, G Henrike Westerveld, Hetty A van den Berg, Annerie Slot, Friederike L A Koppe, Stefan Kommoss, Jan Willem M Mens, Marlies E Nowee, Stefan Bijmolt, David Cibula, Tanja C Stam, Ina M Jurgenliemk-Schulz, An Snyers, Moritz Hamann, Aleida G Zwanenburg, Veronique L M A Coen, Katrien Vandecasteele, Charles Gillham, Cyrus Chargari, Karen W Verhoeven-Adema, Hein Putter, Wilbert B van den Hout, Bastiaan G Wortman, Hans W Nijman, Tjalling Bosse, Carien L Creutzberg

10.1136/ijgc-2020-001929

October 12, 2020

Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal (PROTECTOR): protocol for a prospective non-randomised multi-center trial

Faiza Gaba, Sadiyah Robbani, Naveena Singh, W Glenn McCluggage, Nafisa Wilkinson, Raji Ganesan, Gareth Bryson, Gareth Rowlands, Charlotte Tyson, Rupali Arora, Ertan Saridogan, Helen Hanson, Matthew Burnell, Rosa Legood, D Gareth Evans, Usha Menon, Ranjit Manchanda, on behalf of the PROTECTOR team, Katie Snape, Sadaf Ghaem-Maghami, Gautam Mehra, Angela Brady, Adam Rosenthal, Michelle MacKintosh, Ian Harley, Sudha Sundar, Claire Newton, Omer Devaja, Tim Duncan, Supratik Chattopadhyay, Natalia Povolotskaya, Rema Iyer, Lucy Side, Anil Tailor, Manon van Seters, Suma Kodiathodi, Partha Sengupta, Iain Cameron, Sonali Kaushik, Karin Williamson, Katherine Edey, Sian Taylor, Andrew Phillips, Mark Willett, Tony Chalhoub, Sanjay Rao, Nicholas Matthews, Aarti Sharma, Scott Fegan, Mahalakshmi Gurumurthy, Kalpana Ragupathy, Beena Abdul, Ibraheem Hamoodi, Claire Park, Jane Borley, Richard Hutson, Kerryn Lutchman-Singh, Richard Peevor

10.1136/ijgc-2020-001541

September 8, 2020

Atezolizumab in combination with bevacizumab and chemotherapy versus bevacizumab and chemotherapy in recurrent ovarian cancer – a randomized phase III trial (AGO-OVAR 2.29/ENGOT-ov34)

Philipp Harter, Patricia Pautier, Els Van Nieuwenhuysen, Alexander Reuss, Andres Redondo, Kristina Lindemann, Christian Kurzeder, Edgar Petru, Florian Heitz, Jalid Sehouli, Nikolaus Degregorio, Pauline Wimberger, Alexander Burges, Nadin Cron, Jonathan Ledermann, Domenica Lorusso, Xavier Paoletti, Frederik Marme

10.1136/ijgc-2020-001572

June 30, 2020