Clinical Trial

A phase III, randomized, double blinded trial of platinum based chemotherapy with or without atezolizumab followed by niraparib maintenance with or without atezolizumab in patients with recurrent ovarian, tubal, or peritoneal cancer and platinum treatment free interval of more than 6 months: ENGOT-Ov41/GEICO 69-O/ANITA Trial

Antonio Gonzalez Martin, Luisa Sanchez Lorenzo, Nicoletta Colombo, René dePont Christensen, Florian Heitz, Mihai Meirovitz, Frederic Selle, Toon van Gorp, Nuria Alvarez, Javier Sanchez, Carmen Marqués

10.1136/ijgc-2020-001633

December 14, 2020

ICON 9—an international phase III randomized study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemotherapy

Osnat Elyashiv, Jonathan Ledermann, Gita Parmar, Laura Farrelly, Nicholas Counsell, Amanda Feeney, Fatima El-Khouly, Ian Macdonald, Andreia Neto, Esther Arthur-Darkwa, Eva Burnett, Gordon C Jayson, Linda Mileshkin, Charlie Gourley, Shibani Nicum

10.1136/ijgc-2020-002073

October 23, 2020

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

Anne Sophie V M van den Heerik, Nanda Horeweg, Remi A Nout, Ludy C H W Lutgens, Elzbieta M van der Steen-Banasik, G Henrike Westerveld, Hetty A van den Berg, Annerie Slot, Friederike L A Koppe, Stefan Kommoss, Jan Willem M Mens, Marlies E Nowee, Stefan Bijmolt, David Cibula, Tanja C Stam, Ina M Jurgenliemk-Schulz, An Snyers, Moritz Hamann, Aleida G Zwanenburg, Veronique L M A Coen, Katrien Vandecasteele, Charles Gillham, Cyrus Chargari, Karen W Verhoeven-Adema, Hein Putter, Wilbert B van den Hout, Bastiaan G Wortman, Hans W Nijman, Tjalling Bosse, Carien L Creutzberg

10.1136/ijgc-2020-001929

October 12, 2020

Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal (PROTECTOR): protocol for a prospective non-randomised multi-center trial

Faiza Gaba, Sadiyah Robbani, Naveena Singh, W Glenn McCluggage, Nafisa Wilkinson, Raji Ganesan, Gareth Bryson, Gareth Rowlands, Charlotte Tyson, Rupali Arora, Ertan Saridogan, Helen Hanson, Matthew Burnell, Rosa Legood, D Gareth Evans, Usha Menon, Ranjit Manchanda, on behalf of the PROTECTOR team, Katie Snape, Sadaf Ghaem-Maghami, Gautam Mehra, Angela Brady, Adam Rosenthal, Michelle MacKintosh, Ian Harley, Sudha Sundar, Claire Newton, Omer Devaja, Tim Duncan, Supratik Chattopadhyay, Natalia Povolotskaya, Rema Iyer, Lucy Side, Anil Tailor, Manon van Seters, Suma Kodiathodi, Partha Sengupta, Iain Cameron, Sonali Kaushik, Karin Williamson, Katherine Edey, Sian Taylor, Andrew Phillips, Mark Willett, Tony Chalhoub, Sanjay Rao, Nicholas Matthews, Aarti Sharma, Scott Fegan, Mahalakshmi Gurumurthy, Kalpana Ragupathy, Beena Abdul, Ibraheem Hamoodi, Claire Park, Jane Borley, Richard Hutson, Kerryn Lutchman-Singh, Richard Peevor

10.1136/ijgc-2020-001541

September 8, 2020