User profiles for "author:Yi Zhang"

Yi Zhang

- Verified email at genetics.med.harvard.edu - Cited by 88116

Yi-Cheng Zhang

- Verified email at unifr.ch - Cited by 33974

Toward an aggregated understanding of enzymatic hydrolysis of cellulose: noncomplexed cellulase systems

YHP Zhang, LR Lynd - Biotechnology and bioengineering, 2004 - Wiley Online Library
Abstract Information pertaining to enzymatic hydrolysis of cellulose by noncomplexed
cellulase enzyme systems is reviewed with a particular emphasis on development of …

The diverse functions of histone lysine methylation

C Martin, Y Zhang - Nature reviews Molecular cell biology, 2005 - nature.com
Covalent modifications of histone tails have fundamental roles in chromatin structure and
function. One such modification, lysine methylation, has important functions in many …

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

Y Zhang, D Reinberg - Genes & development, 2001 - genesdev.cshlp.org
In this review, we discuss recent advances made on histone methylation and its diverse
functions in regulating gene expression. Methylation of histone polypeptides might be static …

[HTML][HTML] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

Y Wang, D Zhang, G Du, R Du, J Zhao, Y Jin, S Fu… - The lancet, 2020 - thelancet.com
Background No specific antiviral drug has been proven effective for treatment of patients
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …

Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms

X Jin, JS Lian, JH Hu, J Gao, L Zheng, YM Zhang… - Gut, 2020 - gut.bmj.com
Objective The SARS-CoV-2-infected disease (COVID-19) outbreak is a major threat to
human beings. Previous studies mainly focused on Wuhan and typical symptoms. We …

Dynamic scaling of growing interfaces

M Kardar, G Parisi, YC Zhang - Physical Review Letters, 1986 - APS
A model is proposed for the evolution of the profile of a growing interface. The deterministic
growth is solved exactly, and exhibits nontrivial relaxation patterns. The stochastic version is …

[HTML][HTML] A trial of lopinavir–ritonavir in adults hospitalized with severe Covid-19

B Cao, Y Wang, D Wen, W Liu, J Wang… - New England journal …, 2020 - Mass Medical Soc
Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open …

[HTML][HTML] Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

F Zhou, T Yu, R Du, G Fan, Y Liu, Z Liu, J Xiang… - The lancet, 2020 - thelancet.com
Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak
of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome …

Reproducing kernel particle methods

WK Liu, S Jun, YF Zhang - International journal for numerical …, 1995 - Wiley Online Library
A new continuous reproducing kernel interpolation function which explores the attractive
features of the flexible time-frequency and space-wave number localization of a window …

[PDF][PDF] TBtools: an integrative toolkit developed for interactive analyses of big biological data

C Chen, H Chen, Y Zhang, HR Thomas, MH Frank… - Molecular plant, 2020 - cell.com
The rapid development of high-throughput sequencing techniques has led biology into the
big-data era. Data analyses using various bioinformatics tools rely on programming and …