High-grade gliomas in children are different from those that arise in adults. Recent
collaborative molecular analyses of these rare cancers have revealed previously …

Polyoxometalate–viologen hybrids are a class of photochromic materials with variable
structures and interesting application performance. In recent years, some progress has been …

Diffuse intrinsic pontine glioma (DIPG) is a fatal childhood cancer. We performed a chemical
screen in patient-derived DIPG cultures along with RNA-seq analyses and integrated …

Medulloblastoma, the most common malignant paediatric brain tumour, arises in the
cerebellum and disseminates through the cerebrospinal fluid in the leptomeningeal space to …

The development of targeted anti-cancer therapies through the study of cancer genomes is
intended to increase survival rates and decrease treatment-related toxicity. We treated a …

Medulloblastoma is a malignant childhood cerebellar tumour type that comprises distinct
molecular subgroups. Whereas genomic characteristics of these subgroups are well …

OBJECTIVE Oxidative stress induced by free fatty acids contributes to the development of
cardiovascular diseases in patients with metabolic syndrome. Reducing oxidative stress …

Medulloblastoma (MB) is a highly malignant pediatric brain tumor. Despite aggressive
therapy, many patients succumb to the disease, and survivors experience severe side …

Valproic acid is a well-tolerated anticonvulsant that has been identified recently as a histone
deacetylase inhibitor. To evaluate the antitumor efficacy and mechanisms of action of …

Background: Oxidative stress induced by free fatty acids plays a critical role in the
pathogenesis of endothelial dysfunction and atherosclerosis in patients with metabolic …