The nuclear factor kB (NF-kB) comprises a family of transcription factors involved in the
regulation of a wide variety of biological responses. NF-kB plays a well-known function in …

In the western world, endometrial carcinoma (EC) is the most common cancer of the female
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …

This article reviews the main molecular alterations involved in endometrial carcinoma. Five
molecular features (microsatellite instability, and mutations in the PTEN, k-RAS, PIK3CA and …

In previous studies we have demonstrated that the active form of vitamin D (1, 25 (OH) 2D3)
increases vascular endothelial growth factor (VEGF) expression and release in vascular …

The proper growth and elaboration of neural processes is essential for the establishment of
a functional nervous system during development and is an integral feature of neural …

Alterations in the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway are common
in endometrial carcinoma. Inactivation of the tumor suppressor gene PTEN leads to a …

Endometrial cancer (EC) is the most common gynecologic malignancy of the female genital
tract and the fourth most common neoplasia in women. In EC, myometrial invasion is …

The members of the glial cell line-derived neurotrophic factor (GDNF) family of neurotrophic
factors (GDNF, neurturin, persephin, and artemin) are able to promote in vivo and in vitro …

Netrin-1 is upregulated in cancers as a protumoural mechanism. Here we describe netrin-1
upregulation in a majority of human endometrial carcinomas (ECs) and demonstrate that …

The NF‐κB family of transcription factors regulates a wide variety of cellular processes
including cell growth, differentiation, and apoptosis. A tissue microarray was constructed …