[HTML][HTML] Oleic acid exhibits anti-proliferative and anti-invasive activities via the PTEN/AKT/mTOR pathway in endometrial cancer
B Deng, W Kong, H Suo, X Shen, MA Newton… - Cancers, 2023 - mdpi.com
Simple Summary Metabolic reprogramming, especially fatty acid metabolism, is very
strongly associated with carcinogenesis and progression of endometrial cancer. Increasing …
strongly associated with carcinogenesis and progression of endometrial cancer. Increasing …
[HTML][HTML] An evaluation of the microbiota of the upper reproductive tract of women with and without epithelial ovarian cancer
WR Brewster, WC Burkett, EM Ko, V Bae-Jump… - Gynecologic Oncology …, 2022 - Elsevier
Objective The microbiome of the female upper reproductive tract (URT) has not been
characterized. We hypothesize that distinct bacterial species may be identified in different …
characterized. We hypothesize that distinct bacterial species may be identified in different …
The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches
WC Burkett, AD Clontz, TO Keku… - Biochimica et Biophysica …, 2023 - Elsevier
Endometrial cancer (EC) is the most common gynecologic malignancy in the United States,
and its incidence and mortality are rising. Obesity is more tightly associated with EC than …
and its incidence and mortality are rising. Obesity is more tightly associated with EC than …
A review of current management of placental site trophoblastic tumor and epithelioid trophoblastic tumor
WC Burkett, JT Soper - Obstetrical & Gynecological Survey, 2022 - journals.lww.com
A Review of Current Management of Placental Site Trophoblast... : Obstetrical & Gynecological
Survey A Review of Current Management of Placental Site Trophoblastic Tumor and Epithelioid …
Survey A Review of Current Management of Placental Site Trophoblastic Tumor and Epithelioid …
[HTML][HTML] Differences in the microbial profiles of early stage endometrial cancers between Black and White women
GM Hawkins, WC Burkett, AN McCoy, HB Nichols… - Gynecologic …, 2022 - Elsevier
Objective Black women suffer a higher mortality from endometrial cancer (EC) than White
women. Potential biological causes for this disparity include a higher prevalence of obesity …
women. Potential biological causes for this disparity include a higher prevalence of obesity …
Adjuvant therapy for early stage, endometrial cancer with lymphovascular space invasion: is there a role for chemotherapy?
Objectives Lymphovascular space invasion (LVSI) is an independent risk factor for
recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but …
recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but …
Ipatasertib, an oral AKT inhibitor, in combination with carboplatin exhibits anti-proliferative effects in uterine serous carcinoma
WC Burkett, Z Zhao, MA Newton, W Sun… - Annals of …, 2023 - Taylor & Francis
Purpose Uterine serous carcinoma (USC) exhibits worse survival rates compared to the
endometrioid subtype, and there is currently no effective treatment options for recurrence of …
endometrioid subtype, and there is currently no effective treatment options for recurrence of …
Adjuvant treatment improves overall survival in women with high-intermediate risk early-stage endometrial cancer with lymphovascular space invasion
Background Adjuvant therapy in early-stage endometrial cancer has not shown a clear
overall survival benefit, and hence, patient selection remains crucial. Objective To determine …
overall survival benefit, and hence, patient selection remains crucial. Objective To determine …
Extending the platinum-free interval: the impact of omitting 2nd line platinum chemotherapy in intermediate platinum-sensitive ovarian cancer
LE Dockery, AR Rubenstein, K Ding, SG Mashburn… - Gynecologic …, 2019 - Elsevier
Objectives Patients with epithelial ovarian cancer (EOC) recurring between 6 and 12 months
after primary platinum chemotherapy have worse prognosis than those recurring in> 12 …
after primary platinum chemotherapy have worse prognosis than those recurring in> 12 …
Fractured and delayed: A qualitative analysis of disruptions in care for gynecologic malignancies during incarceration
WC Burkett, Y Iwai, PA Gehrig, AK Knittel - Gynecologic Oncology, 2023 - Elsevier
Objective Women are experiencing growing rates of incarceration at twice the pace of that
for men. Additionally, one-third will be older than 55 years of age by the end of the decade …
for men. Additionally, one-third will be older than 55 years of age by the end of the decade …