The emphasis in contemporary medical oncology has been “precision” or “personalized”
medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar …

OBJECTIVE: To evaluate the safety of fertility-sparing hormonal therapy for endometrial
cancer in young patients. METHODS: We reviewed the clinical and pathologic records of …

Objective A sentinel lymph node biopsy is widely accepted as the standard of care for
surgical staging in low-grade endometrial cancer, but its value in high-grade endometrial …

Purpose Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene, and loss of
function mutations are common and appear to be important in the pathogenesis of …

OBJECTIVE: Metformin, a commonly used drug in the treatment of type II diabetes, may
reduce cancer risk and improve cancer prognosis. We evaluated its effect on epithelial …

The object of this study was to analyze the potential association between the expression of
MMP-2, MMP-9, MT1-MMP and TIMP-2, and disease outcome in advanced-stage ovarian …

Background Targeting of VEGF is a potential therapeutic option in patients with malignant
ovarian ascites. We present the final results of a multicentre study of the efficacy and safety …

PURPOSE To compare the disease-free survival (DFS) between open and minimally
invasive radical hysterectomies (RH) performed in academic medical institutions METHODS …

OBJECTIVE: The aims of the study were to evaluate the ability of metformin to induce
apoptosis in epithelial ovarian cancer cell lines and to identify the pathways involved in this …

BACKGROUND Ovarian tumors of borderline malignancy have a less aggressive behavior
and tend to occur at a younger age than their invasive counterparts. The role and extent of …