User profiles for "author:Travis T Sims"

Travis T. Sims

Assistant Professor of Gynecologic Oncology, The University of Texas MD Anderson Cancer …
Verified email at mdanderson.org
Cited by 436

[HTML][HTML] Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

TT Sims, MB El Alam, TV Karpinets… - Communications …, 2021 - nature.com
Diversity of the gut microbiome is associated with higher response rates for cancer patients
receiving immunotherapy but has not been investigated in patients receiving radiation …

Gut microbial diversity and genus-level differences identified in cervical cancer patients versus healthy controls

TT Sims, LE Colbert, J Zheng, AYD Medrano… - Gynecologic …, 2019 - Elsevier
Objectives The aim of this study was to characterize variation in the gut microbiome of
women with locally advanced cervical cancer and compare it to healthy controls. Methods …

Microbial diversity and composition is associated with patient-reported toxicity during chemoradiation therapy for cervical cancer

A Mitra, GWG Biegert, AY Delgado, TV Karpinets… - International Journal of …, 2020 - Elsevier
Purpose Patients receiving pelvic radiation for cervical cancer experience high rates of
acute gastrointestinal (GI) toxicity. The association of changes in the gut microbiome with …

Treatment perspectives for ovarian cancer in Europe and the United States: initial therapy and platinum-sensitive recurrence after parp inhibitors or bevacizumab …

A Lainé, TT Sims, O Le Saux, I Ray-Coquard… - Current oncology …, 2021 - Springer
Abstract Purpose of Review Although the survival rate of patients with ovarian cancer (OC)
has significantly improved, OC is still one of the most common causes of gynecologic cancer …

Intensified systemic therapy regimens in combination with definitive radiation for treatment of cervical cancer

TT Sims, AH Klopp - Seminars in radiation oncology, 2020 - Elsevier
Definitive standard chemoradiation for locoregionally advanced carcinomas of the uterine
cervix includes multimodality therapy consisting of concurrent cisplatin based …

[HTML][HTML] A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

MB El Alam, TT Sims, R Kouzy, GWG Biegert… - PloS one, 2021 - journals.plos.org
Background A diverse and abundant gut microbiome can improve cancer patients' treatment
response; however, the effect of pelvic chemoradiotherapy (CRT) on gut diversity and …

Classification of high-grade serous ovarian cancer using tumor morphologic characteristics

KF Handley, TT Sims, NW Bateman… - JAMA network …, 2022 - jamanetwork.com
Importance Despite similar histologic appearance among high-grade serous ovarian
cancers (HGSOCs), clinical observations suggest vast differences in gross appearance …

Expansion of Candidate HPV-Specific T Cells in the Tumor Microenvironment during Chemoradiotherapy Is Prognostic in HPV16+ Cancers

LE Colbert, MB El, EJ Lynn, J Bronk, TV Karpinets… - Cancer Immunology …, 2022 - AACR
Human papillomavirus (HPV) infection causes 600,000 new cancers worldwide each year.
HPV-related cancers express the oncogenic proteins E6 and E7, which could serve as tumor …

The significance of para-aortic nodal size and the role of adjuvant systemic chemotherapy in cervical cancer: an institutional experience

DB Manders, TT Sims, A Bailey, L Hwang… - American Journal of …, 2018 - journals.lww.com
Objective: Cervical cancer metastatic to the para-aortic lymph nodes (PALNs) carries a poor
prognosis. Despite extended-field radiation therapy (EFRT), only 30% to 50% of patients will …

Diversity and composition of gut microbiome of cervical cancer patients: Do results of 16S rRNA sequencing and whole genome sequencing approaches align?

G Biegert, MB El Alam, T Karpinets, X Wu… - Journal of …, 2021 - Elsevier
Background Next generation sequencing has progressed rapidly, characterizing microbial
communities beyond culture-based or biochemical techniques. 16S ribosomal RNA gene …