Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

M Clarke, A Mackay, B Ismer, JC Pickles… - Cancer discovery, 2020 - AACR
Infant high-grade gliomas appear clinically distinct from their counterparts in older children,
indicating that histopathologic grading may not accurately reflect the biology of these tumors …

[HTML][HTML] Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

SM Waszak, PA Northcott, I Buchhalter… - The Lancet …, 2018 - thelancet.com
Background Medulloblastoma is associated with rare hereditary cancer predisposition
syndromes; however, consensus medulloblastoma predisposition genes have not been …

Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the …

LM Hoffman, SEM Veldhuijzen van Zanten… - Journal of clinical …, 2018 - ascopubs.org
Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median
survival of< 1 year. The International and European Society for Pediatric Oncology DIPG …

[HTML][HTML] The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial

LB Kilburn, DA Khuong-Quang, JR Hansford, D Landi… - Nature medicine, 2024 - nature.com
BRAF genomic alterations are the most common oncogenic drivers in pediatric low-grade
glioma (pLGG). Arm 1 (n= 77) of the ongoing phase 2 FIREFLY-1 (PNOC026) trial …

Intracranial growing teratoma syndrome (iGTS): an international case series and review of the literature

G Michaiel, D Strother, N Gottardo, U Bartels… - Journal of Neuro …, 2020 - Springer
Purpose Intracranial growing teratoma syndrome (iGTS) is a rare phenomenon of
paradoxical growth of a germ cell tumor (GCT) during treatment despite normalization of …

Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer

DA Caruso, LM Orme, AM Neale, FJ Radcliff… - Neuro …, 2004 - academic.oup.com
We conducted a phase 1 study of 9 pediatric patients with recurrent brain tumors using
monocyte-derived dendritic cells pulsed with tumor RNA to produce antitumor vaccine …

[HTML][HTML] Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

NG Gottardo, JR Hansford, JP McGlade, F Alvaro… - 2014 - Springer
Medulloblastoma is curable in approximately 70% of patients. Over the past decade,
progress in improving survival using conventional therapies has stalled, resulting in reduced …

[HTML][HTML] Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma

R Kumar, KS Smith, M Deng, C Terhune… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed
Medulloblastoma - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Request strategies in Indonesian

T Hassall - Pragmatics. Quarterly Publication of the International …, 1999 - jbe-platform.com
While many studies have examined this important speech act as performed by native
speakers, the range of languages is still relatively small. Requests by native speakers in …

Individual variation in L2 study-abroad outcomes: A case study from Indonesian pragmatics

T Hassall - Multilingua, 2015 - degruyter.com
This is a study of two Australian learners of Indonesian during a short stay abroad. It
examines their contrasting success in acquiring L2 address terms, in tandem with their …