Molecular pathogenesis of endometriosis-associated clear cell carcinoma of the ovary

H Kobayashi, H Kajiwara, S Kanayama… - Oncology …, 2009 - spandidos-publications.com
Epithelial ovarian cancer (EOC) is the leading cause of death in women with gynecological
malignancies. Among EOC, clear cell carcinoma (CCC) and endometrioid adenocarcinoma …

New insights into the pathophysiology of endometriosis: from chronic inflammation to danger signal

H Kajihara, Y Yamada, S Kanayama… - Gynecological …, 2011 - Taylor & Francis
Background. Various theories try to explain the development and progression of
endometriosis, however, no single theory can explain all aspects of this disorder. Gene …

Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain

H Shigetomi, A Onogi, H Kajiwara, S Yoshida… - Inflammation …, 2010 - Springer
Introduction Protease inhibitors, including the Kunitz, Kazal, serpin and mucus families, play
important roles in inhibiting protease activities during homeostasis, inflammation, tissue …

The role of iron in the pathogenesis of endometriosis

H Kobayashi, Y Yamada, S Kanayama… - Gynecological …, 2009 - Taylor & Francis
Background. Endometriosis may cause symptoms including chronic pelvic pain and
infertility, and increases susceptibility to the development of ovarian cancer. Genomic …

Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response

K Naruse, T Sado, T Noguchi, T Tsunemi… - Journal of reproductive …, 2012 - Elsevier
Inflammatory response in preeclampsia (PE) is a key feature in its pathophysiology.
Advanced Glycation Endproducts (AGEs), receptors for AGEs (RAGE), and RAGE ligands …

The role of hepatocyte nuclear factor-1β in the pathogenesis of clear cell carcinoma of the ovary

H Kobayashi, Y Yamada, S Kanayama… - International Journal of …, 2009 - ijgc.bmj.com
Problem: Clear cell carcinoma (CCC) of the ovary has a number of features distinguishing it
from other epithelial ovarian carcinomas (EOC) because of its characteristic histology and …

[HTML][HTML] Evidence for activation of Toll-like receptor and receptor for advanced glycation end products in preterm birth

T Noguchi, T Sado, K Naruse, H Shigetomi… - Mediators of …, 2010 - hindawi.com
Objective. Individuals with inflammation have a myriad of pregnancy aberrations including
increasing their preterm birth risk. Toll-like receptors (TLRs) and receptor for advanced …

Clear cell carcinoma of the ovary: potential pathogenic mechanisms

H Kajihara, Y Yamada, S Kanayama… - Oncology …, 2010 - spandidos-publications.com
Epithelial ovarian cancer (EOC) is the most common cause of gynecological cancer-related
mortality. Clear cell EOC (cEOC) has a number of clinical features distinguishing it from …

Expression profiles of genes involved in poor prognosis of epithelial ovarian carcinoma: a review

S Yoshida, N Furukawa, S Haruta, Y Tanase… - International Journal of …, 2009 - ijgc.bmj.com
Background: Epithelial ovarian cancer (EOC) is the commonest cause of gynecological
cancer-related mortality. Although the prognosis for patients with advanced cancer is poor …

Maternal-fetal distribution and transfer of dioxins in pregnant women in Japan, and attempts to reduce maternal transfer with Chlorella (Chlorella pyrenoidosa) …

S Nakano, T Noguchi, H Takekoshi, G Suzuki… - Chemosphere, 2005 - Elsevier
Dioxins can be transferred from mother to fetus via the placenta, or to nursing infants via
breast milk, potentially causing developmental health problems in children. To assess …