User profiles for "author:T. C. Chang"

Tsung-Cheng Chang

- Verified email at UTSouthwestern.edu - Cited by 20840

Ting Chia Chang

- Verified email at stanford.edu - Cited by 3965

[HTML][HTML] Resistance random access memory

TC Chang, KC Chang, TM Tsai, TJ Chu, SM Sze - Materials Today, 2016 - Elsevier
Non-volatile memory (NVM) will play a decisive role in the development of the next-
generation of electronic products. Therefore, the development of next-generation NVM is …

microRNAs in vertebrate physiology and human disease

TC Chang, JT Mendell - Annu. Rev. Genomics Hum. Genet., 2007 - annualreviews.org
Over the past five years, the importance of a diverse class of 18–24 nucleotide RNA
molecules, known as microRNAs (miRNAs) has increasingly been recognized. These highly …

[HTML][HTML] Developments in nanocrystal memory

TC Chang, FY Jian, SC Chen, YT Tsai - Materials today, 2011 - Elsevier
Flash nonvolatile memory has been widely applied in portable electronic products.
However, traditional flash memory is expected to reach physical limits as its dimensions are …

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

M Pertea, GM Pertea, CM Antonescu, TC Chang… - Nature …, 2015 - nature.com
Methods used to sequence the transcriptome often produce more than 200 million short
sequences. We introduce StringTie, a computational method that applies a network flow …

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

P Gao, I Tchernyshyov, TC Chang, YS Lee, K Kita… - Nature, 2009 - nature.com
Altered glucose metabolism in cancer cells is termed the Warburg effect, which describes
the propensity of most cancer cells to take up glucose avidly and convert it primarily to …

[PDF][PDF] Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

TC Chang, EA Wentzel, OA Kent, K Ramachandran… - Molecular cell, 2007 - cell.com
The p53 tumor suppressor protein is a critical regulator of the cellular response to cancer-
initiating insults such as genotoxic stress. In this report, we demonstrate that microRNAs …

[HTML][HTML] Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

J Kota, RR Chivukula, KA O'Donnell, EA Wentzel… - Cell, 2009 - cell.com
Therapeutic strategies based on modulation of microRNA (miRNA) activity hold great
promise due to the ability of these small RNAs to potently influence cellular behavior. In this …

Widespread microRNA repression by Myc contributes to tumorigenesis

TC Chang, D Yu, YS Lee, EA Wentzel, DE Arking… - Nature …, 2008 - nature.com
The c-Myc oncogenic transcription factor (Myc) is pathologically activated in many human
malignancies. Myc is known to directly upregulate a pro-tumorigenic group of microRNAs …

High-Performance Single Layered WSe2 p-FETs with Chemically Doped Contacts

H Fang, S Chuang, TC Chang, K Takei, T Takahashi… - Nano …, 2012 - ACS Publications
We report high performance p-type field-effect transistors based on single layered
(thickness,∼ 0.7 nm) WSe2 as the active channel with chemically doped source/drain …

PIK3CA as an oncogene in cervical cancer

YY Ma, SJ Wei, YC Lin, JC Lung, TC Chang… - Oncogene, 2000 - nature.com
Amplification of chromosome arm 3q is the most consistent aberration in cervical cancer,
and is implicated in the progression of dysplastic uterine cervical cells into invasive cancer …