[HTML][HTML] Inhalable nanoparticle-based dry powder formulations for respiratory diseases: Challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

[HTML][HTML] Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice

K Levy, S Natarajan, J Wang, S Chow, JT Eggold… - Scientific reports, 2020 - nature.com
Radiation therapy is the most effective cytotoxic therapy for localized tumors. However,
normal tissue toxicity limits the radiation dose and the curative potential of radiation therapy …

Evaluating the toxicity of Triton X-100 to protozoan, fish, and mammalian cells using fluorescent dyes as indicators of cell viability

VR Dayeh, SL Chow, K Schirmer, DH Lynn… - … and Environmental Safety, 2004 - Elsevier
Three viability assays using fluorescent dyes effectively detected a loss of viability in cultures
of three mammalian cell lines (H4IIE, Caco2, and HepG-2), two fish cell lines (RTgill-W1 and …

Adaptive radiation from resource competition in digital organisms

SS Chow, CO Wilke, C Ofria, RE Lenski, C Adami - Science, 2004 - science.org
Species richness often peaks at intermediate productivity and decreases as resources
become more or less abundant. The mechanisms that produce this pattern are not …

[HTML][HTML] Development of therapeutic vaccines for ovarian cancer

S Chow, JS Berek, O Dorigo - Vaccines, 2020 - mdpi.com
Ovarian cancer remains the deadliest of all gynecologic malignancies. Our expanding
knowledge of ovarian cancer immunology has allowed the development of therapies that …

Role of sentinel lymph node biopsy for gynecologic cancers

S Chow, A Karam - Current Opinion in Obstetrics and Gynecology, 2022 - journals.lww.com
SLN evaluation remains standard of care to detect lymph node metastasis in early-staged
endometrial cancer. In cervical cancer, SLN biopsy has been shown to be reliable, while …

Abdominopelvic FLASH irradiation improves PD-1 immune checkpoint inhibition in preclinical models of ovarian cancer

JT Eggold, S Chow, S Melemenidis, J Wang… - Molecular cancer …, 2022 - AACR
Abstract Treatment of advanced ovarian cancer using PD-1/PD-L1 immune checkpoint
blockade shows promise; however, current clinical trials are limited by modest response …

Inhibition of cell proliferation and the action mechanisms of arsenic trioxide (As2O3) on human breast cancer cells

SKY Chow, JYW Chan, KP Fung - Journal of cellular …, 2004 - Wiley Online Library
Abstract Arsenic trioxide (As2O3) is one of the arsenic compounds found in nature. As2O3
has recently been used to treat patients suffering from retinoic acid receptor (AML). It is of …

Trends in the incidence of serous fallopian tube, ovarian, and peritoneal cancer in the US

CI Liao, S Chow, L Chen, DS Kapp, A Mann… - Gynecologic …, 2018 - Elsevier
Objective To identify the trends in incidence of serous fallopian tube, ovarian, and peritoneal
epithelial cancers in the United States. Methods Data was obtained from United States …

Integrated continuous manufacturing of inhalable remdesivir nanoagglomerate dry powders: Design, optimization and therapeutic potential for respiratory viral …

HW Chan, HW Lee, S Chow, DCL Lam… - International Journal of …, 2023 - Elsevier
While inhalable nanoparticle-based dry powders have demonstrated promising potential as
next-generation respiratory medicines, erratic particle redispersibility and poor …