Abstract Recently, thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-
methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer …

In this study, we identified p53 as a novel TCTP-interacting protein using TCTP as bait. Also,
we determined the critical binding sites between TCTP and p53. To elucidate the functional …

The Wnt/β‐catenin signaling pathway is activated during the malignant transformation of
keratinocytes that originate from the human uterine cervix. Dkk1, 2 and 4 have been shown …

Expression of carbonic anhydrase IX (CA9) was shown to be strongly involved in high
incidences of metastasis and poor prognosis in various human tumors. In this study, we …

Cytoplasmic aminoacyl-tRNA synthetases of higher eukaryotes acquired extra peptides in
the course of their evolution. It has been thought that these appendices are related to the …

A series of novel terpyridine-skeleton molecules containing conformational rigidity, 14
containing benzo [4, 5] furo [3, 2-b] pyridine core and 15 comprising chromeno [4, 3-b] …

OBJECTIVE: Thioridazine, a derivative of phenothiazine, has been reported to have
antiproliferative activity on tumor cells. However, the mechanism has not been well defined …

Thioridazine, a member of the phenothiazine family, is a powerful anti-anxiety and anti-
psychotic drug. It can also suppress the growth of several types of tumor in vitro. In the …

CYR61 over-expression promotes cell proliferation by inhibiting carboplatin-induced
apoptosis, decreasing Bax expression, and increasing Bcl-xL, Mcl-1, and Bcl-2. At the same …

Recent studies have shown DAPk as a molecular modulator induced by the second
messenger, responsible for controlling cell destiny decisions, but the detailed mechanism …