User profiles for "author:Robert Tyler Hillman"

Robert Tyler Hillman

The University of Texas MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 1222

Evaluation of PARP and PDL-1 as potential therapeutic targets for women with high-grade neuroendocrine carcinomas of the cervix

MR Carroll, P Ramalingam, G Salvo… - International Journal of …, 2020 - ijgc.bmj.com
Objectives Women with recurrent high-grade neuroendocrine cervical cancer have few
effective treatment options. The aim of this study was to identify potential therapeutic targets …

Impact of a tiered discharge opioid algorithm on prescriptions and patient-reported outcomes after open gynecologic surgery

S Huepenbecker, RT Hillman, MD Iniesta… - International Journal of …, 2021 - ijgc.bmj.com
Objective To compare discharge opioid refills, prescribed morphine equivalent dose and
quantity, and longitudinal patient-reported outcomes before and after implementation of a …

Evaluation of a tiered opioid prescription algorithm in an ERAS pathway: exploring opportunities for further refinement

MS Basabe, TS Suki, MF Munsell, MD Iniesta… - International Journal of …, 2024 - ijgc.bmj.com
Background Opioid over-prescription is wasteful and contributes to the opioid crisis. We
implemented a personalized tiered discharge opioid protocol and education on opioid …

Identification of ovarian high-grade endometrioid-type tumors through multi-omics analysis: JGOG3025-TR2 study

S Takamatsu, RT Hillman, K Yoshihara, T Baba… - medRxiv, 2024 - medrxiv.org
Objective: There is considerable interobserver variability in the differential diagnosis
between ovarian high-grade endometrioid carcinoma (HGEC) and ovarian high-grade …

Assessment of predictive biomarker prevalence in molecularly defined adult-type ovarian granulosa cell tumors.

RT Hillman, DI Lin, DM Gershenson - 2021 - ascopubs.org
5567 Background: The FDA has separately approved pembrolizumab for all advanced solid
tumors with either microsatellite instability or high tumor mutational burden (≥ 10 mutations …

A novel genomic rearrangement signature to predict poor survival among women with high grade serous ovarian cancer.

RT Hillman, KH Lu, PA Futreal - 2017 - ascopubs.org
5509 Background: Resistance to platinum-based chemotherapy is a major cause of disease
progression and mortality among women with high grade serous ovarian cancer (HGSOC). It …

Impact of cytoreductive surgery on survival outcomes for recurrent adult-type granulosa cell tumors of the ovary.

J How, A Flores Legarreta, BM Fellman, K Handley… - 2023 - ascopubs.org
5573 Background: Adult-type granulosa cell tumor of the ovary (aGCT) is a rare tumor that
often relapses and the optimal management strategy is not known. Cytoreductive surgery …

Clinical and genomic landscape of RAS pathway mutations in gynecologic cancers.

J Son, Y Zhang, M Nardo, O Mirallas, RT Hillman… - 2023 - ascopubs.org
5611 Background: We aimed to describe RAS mutations in gynecologic cancers as they
relate to clinicopathologic features, subtypes, co-mutations, and implications for therapy …

Abstract B057: Oncogenic Foxl2 directs enhancer reprogramming and changes in 3D genome structure in ovarian granulosa cell tumors

VK Vuttaradhi, E Khlebus, T Welte, B Lawson… - Cancer Research, 2024 - AACR
Background: Adult-type granulosa cell tumors (aGCTs) are a rare monogenic disease.
Nearly all aGCTs carry a missense point mutation in the Forkhead domain containing …

Utility of surgically documented minimal residual disease as a therapeutic target and early surrogate of frontline treatment outcomes in ovarian cancer.

A Knisely, RN Wilke, BM Fellman, JA Rauh-Hain… - 2023 - ascopubs.org
5549 Background: Cure rates for patients with advanced stage ovarian cancer have not
changed over the last four decades likely due to inability to eradicate residual cancer cells …