ENPP1 immunobiology as a therapeutic target

B Ruiz-Fernández de Córdoba, R Martínez-Monge… - Clinical Cancer …, 2023 - AACR
Abstract ENPP1 (ecto-nucleotide pyrophosphatase/phosphodiesterase) participates in the
hydrolysis of different purine nucleotides in an array of physiologic processes. However …

Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative …

E Villafranca, Y Okruzhnov, MA Dominguez… - Journal of clinical …, 2001 - ascopubs.org
PURPOSE: Thymidylate synthase (TS) is an important target enzyme for the
fluoropyrimidines. TS gene promoter possesses regulatory tandemly repeated (TR) …

[HTML][HTML] Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and …

L Arbea, LI Ramos, R Martínez-Monge, M Moreno… - Radiation …, 2010 - Springer
Purpose To compare target dose distribution, comformality, normal tissue avoidance, and
irradiated body volume (IBV) in 3DCRT using classic anatomical landmarks (c3DCRT) …

CT-guided permanent brachytherapy for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC)

R Martínez-Monge, M Pagola, I Vivas… - Lung cancer, 2008 - Elsevier
Seven patients with early stage T1N0M0 NSCLC who had medical contraindications for
surgical resection were treated with CT-guided percutaneous implantation of 103Pd or 125I …

Tumor ENPP1 (CD203a)/Haptoglobin axis exploits myeloid-derived suppressor cells to promote post-radiotherapy local recurrence in breast cancer

B Ruiz-Fernandez de Cordoba, H Moreno, K Valencia… - Cancer discovery, 2022 - AACR
Locoregional failure (LRF) in patients with breast cancer post-surgery and post-irradiation is
linked to a dismal prognosis. In a refined new model, we identified ectonucleotide …

[HTML][HTML] Salvage brachytherapy in prostate local recurrence after radiation therapy: predicting factors for control and toxicity

I Henríquez, G Sancho, A Hervás, B Guix, J Pera… - Radiation …, 2014 - Springer
Purpose To evaluate efficacy and toxicity after salvage brachytherapy (BT) in prostate local
recurrence after radiation therapy. Methods and materials Between 1993 and 2007, we …

125Iodine brachytherapy for colorectal adenocarcinoma recurrent in the pelvis and paraortics

R Martínez-Monge, S Nag, EW Martin - International Journal of Radiation …, 1998 - Elsevier
Purpose: To evaluate the results of 125I brachytherapy in colorectal cancers recurrent in the
pelvis and paraortics. Methods and Materials: From September 1989 to January 1997, 29 …

Comparison of multimodal therapies and outcomes among patients with high-risk prostate cancer with adverse clinicopathologic features

AU Kishan, RJ Karnes, T Romero, JK Wong… - JAMA network …, 2021 - jamanetwork.com
Importance The optimal management strategy for high-risk prostate cancer and additional
adverse clinicopathologic features remains unknown. Objective To compare clinical …

Surgical resection after preoperative chemoradiotherapy benefits selected patients with unresectable pancreatic cancer

J Aristu, R Cañón, F Pardo… - American journal of …, 2003 - journals.lww.com
Simultaneous chemoradiation is used in unresectable pancreatic cancer for palliation. It is
not known if the use of adjuvant surgery will benefit this group of patients. From November …

External-Beam Radiation Therapy and High–Dose Rate Brachytherapy Combined With Long-Term Androgen Deprivation Therapy in High and Very High Prostate …

R Martínez-Monge, M Moreno, R Ciérvide… - International Journal of …, 2012 - Elsevier
PURPOSE: To determine the feasibility of combined long-term androgen deprivation therapy
(ADT) and dose escalation with high-dose-rate (HDR) brachytherapy. METHODS AND …