Cyclin D1, and to a lesser extent the other D-type cyclins, is frequently deregulated in cancer
and is a biomarker of cancer phenotype and disease progression. The ability of these …

Endocrine therapies targeting oestrogen action (anti-oestrogens, such as tamoxifen, and
aromatase inhibitors) decrease mortality from breast cancer, but their efficacy is limited by …

I. Introduction T HE control of cellular proliferation is known to involve a delicate balance
between the effects of different regulatory molecules including hormones and growth factors …

Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32
recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH …

Examining classic theories, experimental methods, and practical formulas for exploration of
the core topics in nonlinear optics, the second edition of this acclaimed text was extensively …

Cyclins, the regulatory subunits of cyclin-dependent kinases, play an important role in the
control of cellular proliferation. Since dysregulated expression of these genes may …

Genetic alterations in tumor cells often lead to the emergence of growth-stimulatory
autocrine and paracrine signals, involving overexpression of secreted peptide growth …

▪ Abstract The formation of switchable holographic gratings from polymer-dispersed liquid
crystals (H-PDLCs) allows for the development of switchable transmissive and reflective …

We report electrical switching of the diffraction efficiency in volume Bragg gratings written
holographically in polymer-dispersed liquid crystals (PDLCs). Scanning electron microscopy …

There is emerging evidence that the balance between estrogen receptor-α (ERα) and
androgen receptor (AR) signaling is a critical determinant of growth in the normal and …