Real-time near-infrared fluorescence guided surgery in gynecologic oncology: a review of the current state of the art

HJM Handgraaf, FPR Verbeek, QRJG Tummers… - Gynecologic …, 2014 - Elsevier
Near-infrared (NIR) fluorescence imaging has emerged as a promising complimentary
technique for intraoperative visualization of tumor tissue, lymph nodes and vital structures. In …

A novel tumor-specific agent for intraoperative near-infrared fluorescence imaging: a translational study in healthy volunteers and patients with ovarian cancer

CES Hoogstins, QRJG Tummers… - Clinical Cancer …, 2016 - AACR
Purpose: Completeness of cytoreductive surgery is a key prognostic factor for survival in
patients with ovarian cancer. The ability to differentiate clearly between malignant and …

Optimization of near-infrared fluorescence cholangiography for open and laparoscopic surgery

FPR Verbeek, BE Schaafsma, QRJG Tummers… - Surgical …, 2014 - Springer
Background During laparoscopic cholecystectomy, common bile duct (CBD) injury is a rare
but severe complication. To reduce the risk of injury, near-infrared (NIR) fluorescent …

Real-time intraoperative detection of breast cancer using near-infrared fluorescence imaging and Methylene Blue

QRJG Tummers, FPR Verbeek, BE Schaafsma… - European Journal of …, 2014 - Elsevier
Background Despite recent developments in preoperative breast cancer imaging,
intraoperative localization of tumor tissue can be challenging, resulting in tumor-positive …

[HTML][HTML] The value of intraoperative near-infrared fluorescence imaging based on enhanced permeability and retention of indocyanine green: feasibility and false …

QRJG Tummers, CES Hoogstins, AAW Peters… - PloS one, 2015 - journals.plos.org
Objective In ovarian cancer, two of the most important prognostic factors for survival are
completeness of staging and completeness of cytoreductive surgery. Therefore, intra …

[HTML][HTML] Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

QRJG Tummers, CES Hoogstins, KN Gaarenstroom… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Methods Two-to-three hours before surgery 0.1 mg/kg EC17 was intravenously administered
to 12 patients undergoing surgery for ovarian cancer and to 3 patients undergoing surgery …

Intraoperative guidance in parathyroid surgery using near-infrared fluorescence imaging and low-dose Methylene Blue

QRJG Tummers, A Schepers, JF Hamming, J Kievit… - Surgery, 2015 - Elsevier
Background Identification of diseased and normal parathyroid glands during parathyroid
surgery can be challenging. The aim of this study was to assess whether near-infrared (NIR) …

The predictive value of HLA class I tumor cell expression and presence of intratumoral Tregs for chemotherapy in patients with early breast cancer

EM de Kruijf, JGH van Nes, A Sajet, QRJG Tummers… - Clinical cancer …, 2010 - AACR
Purpose: We hypothesized that T-cell immune interaction affects tumor development and
thus clinical outcome. Therefore, we examined the clinical impact of human leukocyte …

Intraoperative near‐infrared fluorescence imaging of parathyroid adenomas with use of low‐dose methylene blue

JR van der Vorst, BE Schaafsma, FPR Verbeek… - Head & …, 2014 - Wiley Online Library
Background Intraoperative identification of parathyroid adenomas can be challenging. We
hypothesized that low‐doses methylene blue (MB) and near‐infrared fluorescence (NIRF) …

Sentinel lymph node biopsy in vulvar cancer using combined radioactive and fluorescence guidance

FPR Verbeek, QRJG Tummers… - International Journal of …, 2015 - ijgc.bmj.com
Objective Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has
recently been introduced to improve the sentinel lymph node (SLN) procedure. Several …