Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses
JS Fleming, CR Beaugié, I Haviv… - Molecular and cellular …, 2006 - Elsevier
Epithelial ovarian cancer (EOC) is often a lethal disease because in many cases early
symptoms go undetected. Although research proceeds apace, as yet there are few reliable …
symptoms go undetected. Although research proceeds apace, as yet there are few reliable …
Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian …
Abstract Kallikrein-related peptidase 7 (KLK7) is upregulated in epithelial ovarian carcinoma
(EOC) with high levels correlated with poor prognosis. However, the mechanisms underlying …
(EOC) with high levels correlated with poor prognosis. However, the mechanisms underlying …
Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?
The kallikrein-related peptidase (KLK) gene family of 15 serine proteases encodes many
proteins, including prostate specific antigen (PSA or KLK3), that are well described and/or …
proteins, including prostate specific antigen (PSA or KLK3), that are well described and/or …
Location of inclusion cysts in mouse ovaries in relation to age, pregnancy, and total ovulation number: implications for ovarian cancer?
OL Tan, PR Hurst, JS Fleming - … of Pathology: A Journal of the …, 2005 - Wiley Online Library
Benign ovarian cysts are thought to be precursor lesions that differentiate and transform into
carcinoma. With the aim of testing the hypothesis that increased ovulation number increases …
carcinoma. With the aim of testing the hypothesis that increased ovulation number increases …
Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphisms in ovarian cancer survival
Introduction: Kallikrein-related peptidase 10 (KLK10) overexpression is a predictor of poor
disease outcome in women with late-stage ovarian cancer. We aimed to identify whether …
disease outcome in women with late-stage ovarian cancer. We aimed to identify whether …
A novel transcript from the KLKP1 gene is androgen regulated, down‐regulated during prostate cancer progression and encodes the first non‐serine protease …
A Kaushal, SA Myers, Y Dong, J Lai, OL Tan… - The …, 2008 - Wiley Online Library
BACKGROUND The kallikrein‐related (KLK) serine protease, prostate specific antigen is the
current marker for prostate cancer (PCa). Other members of the KLK family are also …
current marker for prostate cancer (PCa). Other members of the KLK family are also …
[HTML][HTML] A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival
Background KLK15 over-expression is reported to be a significant predictor of reduced
progression-free survival and overall survival in ovarian cancer. Our aim was to analyse the …
progression-free survival and overall survival in ovarian cancer. Our aim was to analyse the …
Expression of PSA-RP2, an alternatively spliced variant from the PSA gene, is increased in prostate cancer tissues but the protein is not secreted from prostate cancer …
AK Whitbread, TL Veveris-Lowe, Y Dong, OL Tan… - 2010 - degruyter.com
PSA-RP2 is a variant transcript expressed from the PSA gene that is conserved in gorillas,
chimpanzees and humans suggesting a particular relevance for this transcript in these …
chimpanzees and humans suggesting a particular relevance for this transcript in these …