User profiles for "author:O. Takahashi"

Osamu Takahashi

Hiroshima University
Verified email at hiroshima-u.ac.jp
Cited by 5297

Relevance of weak hydrogen bonds in the conformation of organic compounds and bioconjugates: evidence from recent experimental data and high-level ab initio …

O Takahashi, Y Kohno, M Nishio - Chemical reviews, 2010 - ACS Publications
Organic chemists tend to consider the conformation of compounds as a consequence of
repulsive steric interactions. In other words,“the steric effect” means “repulsive” in many …

Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies

AM Ward, O Takahashi, R Stevens… - Journal of …, 2012 - journals.lww.com
Objective: Examine the relationship between home blood pressure (BP) and risk for all-
cause mortality, cardiovascular mortality and cardiovascular events. Methods: We conducted …

Overview of the architecture, circuit design, and physical implementation of a first-generation cell processor

…, DL Stasiak, M Suzuoki, O Takahashi… - IEEE journal of solid …, 2005 - ieeexplore.ieee.org
This paper reviews the design challenges that current and future processors must face, with
stringent power limits, high-frequency targets, and the continuing system integration trends …

Durvalumab with or without tremelimumab for patients with metastatic pancreatic ductal adenocarcinoma: a phase 2 randomized clinical trial

…, A Hezel, SC Chang, G Vlahovic, O Takahashi… - JAMA …, 2019 - jamanetwork.com
Importance New therapeutic options for patients with metastatic pancreatic ductal
adenocarcinoma (mPDAC) are needed. This study evaluated dual checkpoint combination …

The inhomogeneous structure of water at ambient conditions

…, MP Ljungberg, O Takahashi… - Proceedings of the …, 2009 - National Acad Sciences
Small-angle X-ray scattering (SAXS) is used to demonstrate the presence of density
fluctuations in ambient water on a physical length-scale of≈ 1 nm; this is retained with …

Motion planning in a plane using generalized Voronoi diagrams

O Takahashi, RJ Schilling - IEEE Transactions on robotics and …, 1989 - ieeexplore.ieee.org
An algorithm for planning a collision-free path for a rectangle in a planar workspace
populated with polygonal obstacles is presented. Heuristic techniques are used to plan the …

High resolution X-ray emission spectroscopy of liquid water: The observation of two structural motifs

T Tokushima, Y Harada, O Takahashi, Y Senba… - Chemical Physics …, 2008 - Elsevier
The structure of liquid water is presently under intense debate. We summarize the historical
development of the present description of water and the controversy surrounding the X-ray …

Disposition of orally administered 2, 2-Bis (4-hydroxyphenyl) propane (Bisphenol A) in pregnant rats and the placental transfer to fetuses.

O Takahashi, S Oishi - Environmental Health Perspectives, 2000 - ehp.niehs.nih.gov
We studied the disposition of bisphenol A (BPA) in pregnant female F344/DuCrj (Fischer)
rats and its placental transfer to fetuses after a single oral administration of 1 g/kg BPA …

Coronary arterial lesions of Kawasaki disease: cardiac catheterization findings of 1100 cases

…, N Kuwahara, Y Ono, T Kohata, O Takahashi… - Pediatric …, 1986 - Springer
In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for
selective coronary arteriography. Their age at examination ranged from four months to 13 …

Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and mice

O Takahashi, S Oishi - Food and chemical toxicology, 2003 - Elsevier
Male Crj: Wistar rats, HsdHot: Holtzman SD rats, Crj: CD-1 (ICR) mice and C57BL/6CrSlc
mice were administered bisphenol A (BPA) in the diet at a level of 0 (control) and 0.25% for …