Isothermal titration calorimetry (ITC) has become the gold standard for studying molecular
interactions in solution. Although it is increasingly being used in the soft matter and synthetic …

Intrinsically disordered proteins (IDPs) do not have a well-defined structure under
physiological conditions, but they have key roles in cell signaling and regulation, and they …

Background Conformational changes coupled to ligand binding constitute the structural and
energetics basis underlying cooperativity, allostery and, in general, protein regulation …

Epoxy supports (Eupergit C) may be very suitable to achieve the multipoint covalent
attachment of proteins and enzymes, therefore, to stabilize their three-dimensional structure …

Sepabeads‐EP (a new epoxy support) has been utilized to immobilize‐stabilize the enzyme
penicillin G acylase (PGA) via multipoint covalent attachment. These supports are very …

The global health emergency generated by coronavirus disease 2019 (COVID-19) has
prompted the search for preventive and therapeutic treatments for its pathogen, the severe …

Multifunctional supports containing epoxy groups are here proposed as a second
generation of activated supports for covalent immobilization of enzymes following the epoxy …

This paper described that glyoxyl activated supports are only able to quantitatively
immobilize proteins at alkaline pH values and using highly activated supports (otherwise …

New tailor‐made anionic exchange resins have been prepared, based on films of large
polyethylenimine polymers (eg, MW 25,000) completely coating, via covalent immobilization …

The properties of a new commercially available amino-epoxy support (amino-epoxy-
Sepabeads) for immobilizing enzymes have been compared to those of conventional epoxy …