Endometriosis, characterized by the presence of extra-uterine endometrium, is a common
gynecologic disorder in reproductive-age women. Although the detailed molecular …

Non-thermal atmospheric pressure plasma has been widely used for preclinical studies in
areas such as wound healing, blood coagulation, and cancer therapy. We previously …

Cancer therapy consists of multidisciplinary treatment combining surgery, chemotherapy,
radiotherapy, and immunotherapy. Despite the elucidation of cancer mechanisms by …

The biological function of non-thermal atmospheric pressure plasma has been widely
accepted in several types of cancer. We previously developed plasma-activated medium …

Ovarian cancer (OvCa), a lethal gynecological malignancy, disseminates to the peritoneum.
Mesothelial cells (MCs) act as barriers in the abdominal cavity, preventing the adhesion of …

Ovarian cancer is a highly invasive and metastatic disease with a poor prognosis if
diagnosed at an advanced stage, which is often the case. Recent studies argue that ovarian …

Epithelial ovarian cancer (EOC) is considered to secrete various factors in order to promote
peritoneal dissemination through cell-to-cell interaction between cancer and mesothelial …

Background Malignant ovarian germ cell tumors usually occur in young women. Until the
1970s, before establishment of systemic chemotherapy, malignant ovarian germ cell tumors …

Simple Summary Ovarian cancer is among the most malignant gynecologic cancers, in part
because intraperitoneal recurrence occurs with high frequency due to occult metastasis. We …

The mesothelium, covered by a continuous monolayer of mesothelial cells, is the first
protective barrier against metastatic ovarian cancer. However, mesothelial cells release …