Screening for ovarian cancer: a pilot randomised controlled trial

IJ Jacobs, SJ Skates, N MacDonald, U Menon… - The Lancet, 1999 - thelancet.com
Background The value of screening for ovarian cancer is uncertain. We did a pilot
randomised trial to assess multimodal screening with sequential CA 125 antigen and …

PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma

HB Salvesen, N MacDonald, A Ryan… - … journal of cancer, 2001 - Wiley Online Library
Loss of heterozygosity and mutations in the PTEN (MMAC1) tumor suppressor gene are
frequent in endometrial carcinoma. Promoter hypermethylation has recently been identified …

Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women.

SJ Skates, U Menon, N MacDonald… - Journal of clinical …, 2003 - europepmc.org
Purpose Previous studies of CA-125 levels from screening trials for ovarian cancer have
indicated that serial CA-125 levels may identify cases better than a fixed CA-125 cutoff. We …

[PDF][PDF] Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer

U Menon, SJ Skates, S Lewis, AN Rosenthal… - J Clin …, 2005 - researchgate.net
Prospective Study Using the Risk of Ovarian Cancer Algorithm to Screen for Ovarian Cancer
Page 1 Prospective Study Using the Risk of Ovarian Cancer Algorithm to Screen for Ovarian …

Mutations in the autoregulatory domain of β‐tubulin 4a cause hereditary dystonia

J Hersheson, NE Mencacci, M Davis… - Annals of …, 2013 - Wiley Online Library
Dystonia type 4 (DYT4) was first described in a large family from Heacham in Norfolk with an
autosomal dominantly inherited whispering dysphonia, generalized dystonia, and a …

Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas

ND MacDonald, HB Salvesen, A Ryan, OE Iversen… - Cancer research, 2000 - AACR
The replication error repair (RER) phenotype has been reported in 9–43% of sporadic
endometrial carcinomas, but there are conflicting data about its effect on prognosis in this …

Methylation of hMLH1 in a Population-based Series of Endometrial Carcinomas

HB Salvesen, N MacDonald, A Ryan, OE Iversen… - Clinical cancer …, 2000 - AACR
Microsatellite instability (MSI) is a characteristic feature of hereditary nonpolyposis colorectal
cancer and is also observed in sporadic colorectal and endometrial cancers. Alterations in …

Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression

HB Salvesen, I Stefansson… - International …, 2004 - spandidos-publications.com
Mutations in the PTEN gene are frequent in endometrial carcinoma. PTEN methylation is an
alternative mechanism of gene inactivation. To elucidate different mechanisms of PTEN …

[HTML][HTML] A cohort study of 30 day mortality after NON-EMERGENCY surgery in a COVID-19 cold site

V Kasivisvanathan, J Lindsay… - International Journal of …, 2020 - Elsevier
Background Two million non-emergency surgeries are being cancelled globally every week
due to the COVID-19 pandemic, which will have a major impact on patients and healthcare …

Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening

U Menon, A Talaat, AN Rosenthal… - … Journal of Obstetrics …, 2000 - Wiley Online Library
Objective To assess the performance of ultrasonography in a multimodal ovarian cancer
screening strategy. Design Prospective ovarian cancer screening trial between December …