[HTML][HTML] TGF-β: from latent to active

N Khalil - Microbes and infection, 1999 - Elsevier
The transforming growth factor-betas (TGF-βs) are synthesized as precursor proteins that
are modified intracellularly prior to secretion. One of the most relevant intracellular …

Colloidal carriers for ophthalmic drug delivery

RM Mainardes, MCC Urban, PO Cinto… - Current drug …, 2005 - ingentaconnect.com
To achieve effective drug concentration at the intended site for a sufficient period of time is a
requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor …

The role of TGF‐β in pulmonary fibrosis

N Khalil, AH Greenberg - … 157‐Clinical Applications of TGF‐β …, 2007 - Wiley Online Library
Pulmonary fibrosis is an irreversible accumulation of connective tissue in the interstitium of
the lung. The pathogenesis of pulmonary fibrosis is not well understood. Research on …

American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias

…, I Johnston, DS Kim, N Khalil… - … of respiratory and …, 2002 - mayoclinic.elsevierpure.com
Despite the considerable progress in the classification of the idiopathic interstitial
pneumonias (IIPs), the lack of an international standard has resulted in variable and …

Quantum chemical approach of corrosion inhibition

N Khalil - Electrochimica Acta, 2003 - Elsevier
An examination of quantum chemical and corrosion inhibition studies were made to see if
any clear links exist between the two. The results of quantum chemical calculations and …

Increased production and immunohistochemical localization of transforming growth factor-b in idiopathic pulmonary fibrosis

N Khalil, RN O'Connor, HW Unruh… - Am J Respir Cell Mol …, 1991 - atsjournals.org
Transforming growth factor-S (TGF-I3) can regulate cell growth and differentiation as well as
production of extracellular matrix proteins. Elevated production ofTGF-13 has been …

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

N Khalil, O Bereznay, M Sporn… - The Journal of …, 1989 - rupress.org
A rat model of bleomycin-induced pulmonary inflammation and fibrosis was used to examine
the relationship between collagen synthesis and transforming growth factor beta (TGF-beta) …

TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study.

N Khalil, RN O'Connor, KC Flanders… - American journal of …, 1996 - atsjournals.org
Although it is recognized that three isoforms of transforming growth factor-beta (TGF-beta)
exist in mammals, their expression, distribution, and function in injury and repair are not well …

Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial

…, L Richeldi, J De Andrade, N Khalil… - Annals of internal …, 2013 - acpjournals.org
Chinese translation This article has been corrected. The original version (PDF) is appended
to this article as a Supplement. Background: Idiopathic pulmonary fibrosis (IPF) is …

Pharmacokinetics of curcumin-loaded PLGA and PLGA–PEG blend nanoparticles after oral administration in rats

NM Khalil, TCF do Nascimento, DM Casa… - Colloids and Surfaces B …, 2013 - Elsevier
The aim of this study was to assess the potential of nanoparticles to improve the
pharmacokinetics of curcumin, with a primary goal of enhancing its bioavailability. Polylactic …