DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the …

DF Peng, Y Kanai, M Sawada, S Ushijima… - …, 2006 - academic.oup.com
To evaluate the significance of alterations in DNA methylation during multistage
carcinogenesis of the pancreas, tissue samples of 13 peripheral pancreatic duct epithelia …

[HTML][HTML] Evolutionary histories of breast cancer and related clones

T Nishimura, N Kakiuchi, K Yoshida, T Sakurai… - Nature, 2023 - nature.com
Recent studies have documented frequent evolution of clones carrying common cancer
mutations in apparently normal tissues, which are implicated in cancer development …

Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas

DF Peng, Y Kanai, M Sawada, S Ushijima… - Cancer …, 2005 - Wiley Online Library
Aberrant DNA methylation has been shown to play an important role during multistage
carcinogenesis in various human organs. The aim of the present study was to evaluate the …

Different expression patterns of KIT, EGFR, and HER‐2 (c‐erbB‐2) oncoproteins between epithelial and mesenchymal components in uterine carcinosarcoma

M Sawada, H Tsuda, M Kimura, S Okamoto… - Cancer …, 2003 - Wiley Online Library
Uterine carcinosarcoma histologically comprises the components of epithelial and
mesenchymal malignancies, and is known to be clinically highly aggressive. To reveal the …

Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion

M Sawada, Y Kanai, E Arai, S Ushijima, H Ojima… - Cancer letters, 2007 - Elsevier
Aberrant DNA methylation has been shown to play important roles during multistage
carcinogenesis in various human organs. The aim of this study was to evaluate the …

Radical hysterectomy for FIGO stage IIB cervical cancer: clinicopathological characteristics and prognostic evaluation

T Kasamatsu, T Onda, M Sawada, T Kato, S Ikeda - Gynecologic oncology, 2009 - Elsevier
OBJECTIVE: To clarify the clinicopathological features and prognostic factors of patients with
FIGO stage IIB cervical cancer who were treated with radical hysterectomy. METHODS: One …

Neoadjuvant weekly carboplatin and paclitaxel followed by radical hysterectomy for locally advanced cervical cancer: long-term results

T Mori, K Hosokawa, M Sawada, H Kuroboshi… - International Journal of …, 2010 - ijgc.bmj.com
Introduction: To determine the long-term effect of neoadjuvant chemotherapy with paclitaxel
and carboplatin on a weekly schedule followed by radical surgery for patients with locally …

Versatile lotus petal flap for vulvoperineal reconstruction after gynecological ablative surgery

M Sawada, Y Kimata, T Kasamatsu, T Yasumura… - Gynecologic …, 2004 - Elsevier
OBJECTIVE.: The objective of the present work was to assess the efficacy and complications
of the use of the lotus petal flap in the vulvoperineal reconstruction among female patients …

Estrogen-related receptor-γ regulates estrogen receptor-α responsiveness in uterine endometrial cancer

T Yamamoto, T Mori, M Sawada, H Kuroboshi… - International Journal of …, 2012 - ijgc.bmj.com
Objective Estrogen-related receptors (ERRs) are orphan nuclear receptors that modulate the
estrogen receptor (ER)-mediated pathway and play roles in the regulation of breast and …

Multi‐institutional phase II study of neoadjuvant irinotecan and nedaplatin followed by radical hysterectomy and the adjuvant chemotherapy for locally advanced, bulky …

T Mori, H Makino, T Okubo, Y Fujiwara… - Journal of Obstetrics …, 2019 - Wiley Online Library
Aim A multi‐institutional phase II trial was conducted to determine the efficacy and toxicity of
neoadjuvant chemotherapy with irinotecan and nedaplatin followed by radical hysterectomy …