In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …

Background ACE inhibitors are widely prescribed for hypertension so it is essential to
determine and compare their effects on blood pressure (BP), heart rate and withdrawals due …

Background Angiotensin receptor blockers (ARBs) are widely prescribed for hypertension so
it is essential to determine and compare their effects on blood pressure (BP), heart rate and …

Methods| From January 24 to February 4, 2020, 3 patients at the dedicated SARS-CoV-2
outbreak center in Singapore in airborne infection isolation rooms (12 air exchanges per …

Environmental exposure to active pharmaceutical ingredients (APIs) can have negative
effects on the health of ecosystems and humans. While numerous studies have monitored …

Genome-wide association studies suggest that common genetic variants explain only a
modest fraction of heritable risk for common diseases, raising the question of whether rare …

Understanding the particle size distribution in the air and patterns of environmental
contamination of SARS-CoV-2 is essential for infection prevention policies. Here we screen …

Toll-like receptors (TLRs) and the downstream adaptor molecule myeloid differentiation
factor 88 (MyD88) play an essential role in the innate immune responses. Here, we …

Advanced malignancy in tumours represents the phenotypic end-point of successive genetic
lesions that affect the function and regulation of oncogenes and tumour-suppressor genes …

Glioblastomas are highly malignant tumors of the central nervous system that are resistant to
radiation and chemotherapy [1]. We explored the role of the phosphatidylinositol (PI) 3 …