User profiles for "author:Merryn Voysey"

Merryn Voysey

Senior Statistician, University of Oxford
Verified email at paediatrics.ox.ac.uk
Cited by 34131

[HTML][HTML] External validation of multivariable prediction models: a systematic review of methodological conduct and reporting

GS Collins, JA de Groot, S Dutton, O Omar… - BMC medical research …, 2014 - Springer
Background Before considering whether to use a multivariable (diagnostic or prognostic)
prediction model, it is essential that its performance be evaluated in data that were not used …

[HTML][HTML] Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South …

M Voysey, SAC Clemens, SA Madhi, LY Weckx… - The Lancet, 2021 - thelancet.com
Background A safe and efficacious vaccine against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control …

[HTML][HTML] Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled …

PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker… - The Lancet, 2020 - thelancet.com
Background The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and …

[HTML][HTML] Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

S Feng, DJ Phillips, T White, H Sayal, PK Aley, S Bibi… - Nature medicine, 2021 - nature.com
The global supply of COVID-19 vaccines remains limited. An understanding of the immune
response that is predictive of protection could facilitate rapid licensure of new vaccines. Data …

[HTML][HTML] Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind …

MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman… - The Lancet, 2020 - thelancet.com
Background Older adults (aged≥ 70 years) are at increased risk of severe disease and
death if they develop COVID-19 and are therefore a priority for immunisation should an …

[PDF][PDF] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses

W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa… - Cell, 2022 - cell.com
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B. 1.1.
529 was announced, containing far more mutations in Spike (S) than previously reported …

[HTML][HTML] Efficacy of the ChAdOx1 nCoV-19 Covid-19 vaccine against the B. 1.351 variant

SA Madhi, V Baillie, CL Cutland… - … England Journal of …, 2021 - Mass Medical Soc
Background Assessment of the safety and efficacy of vaccines against the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in different populations is essential, as is …

[HTML][HTML] Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a …

M Voysey, SAC Clemens, SA Madhi, LY Weckx… - The Lancet, 2021 - thelancet.com
Summary Background The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for
emergency use by the UK regulatory authority, Medicines and Healthcare products …

Inhaled nitric oxide in preterm infants: an individual-patient data meta-analysis of randomized trials

LM Askie, RA Ballard, GR Cutter, C Dani… - …, 2011 - publications.aap.org
BACKGROUND: Inhaled nitric oxide (iNO) is an effective therapy for pulmonary
hypertension and hypoxic respiratory failure in term infants. Fourteen randomized controlled …

[HTML][HTML] The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials.

B Mihaylova, J Emberson, L Blackwell… - Lancet (London …, 2012 - europepmc.org
Background Statins reduce LDL cholesterol and prevent vascular events, but their net effects
in people at low risk of vascular events remain uncertain. Methods This meta-analysis …