Background Missing outcome data is a threat to the validity of treatment effect estimates in
randomized controlled trials. We aimed to evaluate the extent, handling, and sensitivity …

Abstract Background Cluster randomized trials (CRTs) randomize participants in groups,
rather than as individuals and are key tools used to assess interventions in health research …

Background. Many commercially available pedometers undercount, especially at slower
speeds. We examined the effects of age, obesity, and self-selected walking speed on …

Dropout in randomised controlled trials is common and threatens the validity of results, as
completers may differ from people who drop out. Differing dropout rates between treatment …

Background/aims: Generalized estimating equations are a common modeling approach
used in cluster randomized trials to account for within-cluster correlation. It is well known that …

Clinical presentation, outcomes, and duration of COVID-19 has ranged dramatically. While
some individuals recover quickly, others suffer from persistent symptoms, collectively known …

Patient-reported outcomes are increasingly used in health research, including randomized
controlled trials and observational studies. However, the validity of results in longitudinal …

Missing data are ubiquitous in medical research. Although there is increasing guidance on
how to handle missing data, practice is changing slowly and misapprehensions abound …

Background Although the effects of resistant starch (RS) on postprandial glycemia and
insulinemia have been extensively studied, little is known about the impact of RS on fat …

Background A pilot study can be an important step in the assessment of an intervention by
providing information to design the future definitive trial. Pilot studies can be used to …