Purpose: To evaluate the efficacy of the aromatase inhibitor letrozole in preselected
estrogen receptor (ER)–positive relapsed epithelial ovarian cancer patients and to identify …

Background Small cell lung carcinoma (SCLC) continues to have a poor prognosis, with a 2-
year survival of< 20%. Studies have suggested that SCLC may affect the immune system to …

5528 Background: Advanced mEOC responds poorly to standard therapy. It comprises< 8%
pts in ovarian cancer trials, so it is difficult to examine treatment effects in this subgroup. We …

Objectives The role of endocrine therapy (ET) in high grade serous ovarian carcinoma
(HGSOC) is poorly defined due to the lack of phase III data and significant heterogeneity of …

Reversal of Dose-Limiting Carboplatin-Induced Peripheral Neuropathy with TRPM8
Activator, Menthol, Enables Further Effective Che verified by the presence of a small blob of …

Background: The pathogenesis of brain metastasis as a relatively rare complication of
epithelial ovarian cancer is poorly understood. Some observations suggest that brain …

5571 Background: Ovarian cancer patients with germline BRCA1 or BRCA2 (gBRCA1/2)
mutations frequently respond to multiple lines of chemotherapy. Having noticed significant …

e21553 Background: Patient surveys and patient complaints have been extensively studied
by healthcare services in order to gain feedback to improve patient care. However, analysis …

5553 Background: Endometrioid ovarian carcinomas (EC) have been historically under-
investigated. We sought to determine the molecular landscape of contemporarily defined EC …