S ociety of G ynecologic O ncology recommendations for the prevention of ovarian cancer
JL Walker, CB Powell, L Chen, J Carter, VL Bae Jump… - Cancer, 2015 - Wiley Online Library
Mortality from ovarian cancer may be dramatically reduced with the implementation of
attainable prevention strategies. The new understanding of the cells of origin and the …
attainable prevention strategies. The new understanding of the cells of origin and the …
[PDF][PDF] SATB1 expression governs epigenetic repression of PD-1 in tumor-reactive T cells
TL Stephen, KK Payne, RA Chaurio, MJ Allegrezza… - Immunity, 2017 - cell.com
Despite the importance of programmed cell death-1 (PD-1) in inhibiting T cell effector
activity, the mechanisms regulating its expression remain poorly defined. We found that the …
activity, the mechanisms regulating its expression remain poorly defined. We found that the …
[PDF][PDF] Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression
TL Stephen, MR Rutkowski, MJ Allegrezza… - Immunity, 2014 - cell.com
Tumor-reactive T cells become unresponsive in advanced tumors. Here we have
characterized a common mechanism of T cell unresponsiveness in cancer driven by the …
characterized a common mechanism of T cell unresponsiveness in cancer driven by the …
NAMPT inhibition suppresses cancer stem-like cells associated with therapy-induced senescence in ovarian cancer
T Nacarelli, T Fukumoto, JA Zundell, N Fatkhutdinov… - Cancer research, 2020 - AACR
Epithelial ovarian cancer (EOC) is the most lethal of gynecologic malignancies. The
standard-of-care treatment for EOC is platinum-based chemotherapy such as cisplatin …
standard-of-care treatment for EOC is platinum-based chemotherapy such as cisplatin …
[PDF][PDF] Satb1 overexpression drives tumor-promoting activities in cancer-associated dendritic cells
AJ Tesone, MR Rutkowski, E Brencicova, N Svoronos… - Cell reports, 2016 - cell.com
Special AT-rich sequence-binding protein 1 (Satb1) governs genome-wide transcriptional
programs. Using a conditional knockout mouse, we find that Satb1 is required for normal …
programs. Using a conditional knockout mouse, we find that Satb1 is required for normal …
[PDF][PDF] EZH2 inhibition sensitizes CARM1-high, homologous recombination proficient ovarian cancers to PARP inhibition
In response to DNA double-strand breaks, MAD2L2-containing shieldin complex plays a
critical role in the choice between homologous recombination (HR) and non-homologous …
critical role in the choice between homologous recombination (HR) and non-homologous …
[HTML][HTML] ARID1A promotes genomic stability through protecting telomere cohesion
ARID1A inactivation causes mitotic defects. Paradoxically, cancers with high ARID1A
mutation rates typically lack copy number alterations (CNAs). Here, we show that ARID1A …
mutation rates typically lack copy number alterations (CNAs). Here, we show that ARID1A …
[HTML][HTML] CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer
B Singha, SL Harper, AR Goldman, BG Bitler… - Scientific reports, 2018 - nature.com
New plasma and tissue biomarkers of epithelial ovarian cancer (EOC) could improve early
diagnosis and post-diagnosis clinical management. Here we investigated tissue staining …
diagnosis and post-diagnosis clinical management. Here we investigated tissue staining …
Morcellation and the incidence of occult uterine malignancy: a dual-institution review
TM Picerno, MN Wasson, ARG Rios… - International Journal of …, 2016 - ijgc.bmj.com
Objectives To determine the incidence of unsuspected uterine sarcoma (UtSarc), other
uterine malignancies, and potential malignancies at the time of hysterectomy or …
uterine malignancies, and potential malignancies at the time of hysterectomy or …
Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer
ER Smith, ME Borowsky, VD Jain - Obstetrics & Gynecology, 2013 - journals.lww.com
BACKGROUND: Ovarian cancer diagnosed in pregnancy is rare. There is limited evidence
to guide the choice of optimal chemotherapeutic management for treatment of disease …
to guide the choice of optimal chemotherapeutic management for treatment of disease …