The fallopian tube,“precursor escape” and narrowing the knowledge gap to the origins of high-grade serous carcinoma

TR Soong, BE Howitt, N Horowitz, MR Nucci… - Gynecologic …, 2019 - Elsevier
Most ovarian carcinomas are high-grade serous carcinomas (HGSC) that contain TP53
mutations, present at advanced stage, and eventually become resistant to chemotherapy …

Endometrial stromal sarcoma–the new genetic paradigm

CH Lee, MR Nucci - Histopathology, 2015 - Wiley Online Library
Endometrial stromal sarcoma (ESS) is a gynaecological sarcoma that is composed of cells
that resemble those of proliferative‐phase endometrial stroma. The 2014 World Health …

Mesonephric proliferations of the female genital tract

BE Howitt, MR Nucci - Pathology, 2018 - Elsevier
The mesonephric (Wolffian) duct regresses in females during embryological development.
Remnants of this duct may persist typically along the lateral walls of the cervix, vagina …

A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer

M Herfs, Y Yamamoto, A Laury… - Proceedings of the …, 2012 - National Acad Sciences
Infection by carcinogenic human papillomaviruses (HPV) results in precancers [cervical
intraepithelial neoplasia (CIN)] and cancers near the ectoendocervical squamocolumnar …

Prediction of DNA repair inhibitor response in short-term patient-derived ovarian cancer organoids

SJ Hill, B Decker, EA Roberts, NS Horowitz, MG Muto… - Cancer discovery, 2018 - AACR
Based on genomic analysis, 50% of high-grade serous ovarian cancers (HGSC) are
predicted to have DNA repair defects. Whether this substantial subset of HGSCs actually …

[BOOK][B] Diagnostic gynecologic and obstetric pathology E-book

CP Crum, KR Lee, MR Nucci, SR Granter, BE Howitt… - 2017 - books.google.com
Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text
covers the full range of obstetric and gynecologic pathology, including information on …

Cellular angiofibroma: a benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma

MR Nucci, SR Granter… - The American journal of …, 1997 - journals.lww.com
Four cases of a distinctive soft-tissue tumor of the vulva are described. They were
characterized by occurrence in middle-aged women (39-50 years), small size (< 3 cm), and …

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor

CH Lee, A Mariño-Enriquez, W Ou, M Zhu… - The American journal …, 2012 - journals.lww.com
Endometrial stromal sarcoma (ESS) is a genetically heterogenous group of uterine
sarcomas, of which almost half are associated with JAZF1 rearrangement. We recently …

Serous carcinogenesis in the fallopian tube: a descriptive classification

E Jarboe, A Folkins, MR Nucci… - International Journal …, 2008 - journals.lww.com
The fimbria is the most common site of early serous cancer (tubal intraepithelial carcinoma
or STIC) in women with BRCA mutations (BRCA+). A candidate serous cancer precursor-the …

14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma

CH Lee, WB Ou, A Mariño-Enriquez… - Proceedings of the …, 2012 - National Acad Sciences
14-3-3 proteins are ubiquitously expressed regulators of various cellular functions, including
proliferation, metabolism, and differentiation, and altered 14-3-3 expression is associated …