The clinical pharmacology of etoposide and teniposide

PI Clark, ML Slevin - Clinical pharmacokinetics, 1987 - Springer
Etoposide and teniposide are semisynthetic derivatives of podophyllotoxin and are
increasingly used in cancer medicine. Teniposide is more highly protein-bound than …

The clinical pharmacology of etoposide

ML Slevin - Cancer, 1991 - Wiley Online Library
Etoposide, a semisynthetic derivative of podophyllotoxin, is increasingly used to treat
cancer. Etoposide is a phase‐specific, cytotoxic drug acting in the late S and early G2 …

Attitudes to chemotherapy: comparing views of patients with cancer with those of doctors, nurses, and general public.

ML Slevin, L Stubbs, HJ Plant, P Wilson… - British Medical …, 1990 - bmj.com
OBJECTIVE--To compare responses of patients with cancer with those of a matched control
group, cancer specialists, general practitioners, and cancer nurses in assessing personal …

Who should measure quality of life, the doctor or the patient?

ML Slevin, H Plant, D Lynch, J Drinkwater… - British journal of …, 1988 - nature.com
The extent to which a doctor or health professional can make a valid assessment of a
patient's quality of life, anxiety and depression was investigated in a series of cancer …

Morphine intoxication in renal failure: the role of morphine-6-glucuronide.

RJ Osborne, SP Joel, ML Slevin - Br Med J (Clin Res Ed), 1986 - bmj.com
Patients with impaired renal function may experience severe and prolonged respiratory
depression when treated with morphine. This has been attributed to accumulation of the …

Pursuit and practice of complementary therapies by cancer patients receiving conventional treatment

SM Downer, MM Cody, P McCluskey, PD Wilson… - Bmj, 1994 - bmj.com
Objectives: To determine what proportion of oncology patients receiving conventional
medical treatment also use complementary treatments; to assess which complementary …

Emotional support for cancer patients: what do patients really want?

ML Slevin, SE Nichols, SM Downer, P Wilson… - British journal of …, 1996 - nature.com
For many cancer patients and their families the experience of cancer is an intensely stressful
one. Emotional support is important for most cancer patients during their illness and can be …

Cancer information: a cost-effective intervention

J Mossman, M Boudioni, ML Slevin - European Journal of Cancer, 1999 - Elsevier
There is a considerable knowledge base about the information needs of patients with cancer
(and their relatives and friends). Those needs will vary according to the disease, the stage of …

Measuring cytokine levels in blood. Importance of anticoagulants, processing, and storage conditions.

PW Thavasu, S Longhurst, SP Joel… - Journal of …, 1992 - europepmc.org
The stability and recovery of six human recombinant cytokines (tumour necrosis factor (TNF),
interferon-alpha (IFN-alpha), IFN-gamma, interleukin-1 alpha (IL-1 alpha), IL-1 beta, and IL …

A randomized trial to evaluate the effect of schedule on the activity of etoposide in small-cell lung cancer.

ML Slevin, PI Clark, SP Joel, S Malik… - Journal of Clinical …, 1989 - ascopubs.org
Etoposide is an increasingly used and well-tolerated drug in cancer medicine. Its cytotoxic
action is phase-specific and it has demonstrated schedule dependency in both in vitro and …