It is postulated that localized tissue oxidative stress is a key component in the development
of diabetic nephropathy. There remains controversy, however, as to whether this is an early …

Nowadays, most nurses, pre-and post-qualification, will be required to undertake a literature
review at some point, either as part of a course of study, as a key step in the research …

As with a quantitative study, critical analysis of a qualitative study involves an in-depth
review of how each step of the research was undertaken. Qualitative and quantitative …

Background The one-to-one interview is a commonly used data collection method in health
and social research. Increasing attention has been given in the literature to the process of …

RECORDS of hemispheric average temperatures from land regions for the past 100 years
provide crucial input to the debate over global warming1–4. Despite careful use of the basic …

Heteropolysaccharides, based on a backbone structure of β-1, 4-linked smallcapD-xylose
residues, and collectively referred to as the β-1, 4-smallcapD-xylans, constitute the main …

Damaged mitochondria generate an excess of superoxide, which may mediate tissue injury
in diabetes. We hypothesized that in diabetic nephropathy, advanced glycation end …

OBJECTIVE—Activation of the receptor for advanced glycation end products (RAGE) in
diabetic vasculature is considered to be a key mediator of atherogenesis. This study …

OBJECTIVE Progressive fibrosis in the diabetic kidney is driven and sustained by a diverse
range of profibrotic factors. This study examines the critical role of microRNAs (miRNAs) in …

OBJECTIVE—Excessive production of reactive oxygen species (ROS) via NADPH oxidase
has been implicated in the pathogenesis of diabetic nephropathy. Since NADPH oxidase …