[HTML][HTML] Trastuzumab emtansine for HER2-positive advanced breast cancer

…, D Miles, L Gianni, IE Krop, M Welslau… - New England journal …, 2012 - Mass Medical Soc
Background Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate incorporating
the human epidermal growth factor receptor 2 (HER2)–targeted antitumor properties of …

Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre …

…, C Losem, D Kofahl-Krause, G Heil, M Welslau… - The Lancet, 2013 - thelancet.com
Background Rituximab plus chemotherapy, most often CHOP (cyclophosphamide,
doxorubicin, vincristine, and prednisone), is the first-line standard of care for patients with …

Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphoma

…, SE Al-Batran, SZ Kim, M Welslau… - Journal of Clinical …, 2005 - ascopubs.org
Purpose The aim of this multicenter-study was to evaluate the progression-free survival,
response rate and toxicity of the combination of bendamustine and rituximab (BR) in patients …

Trastuzumab emtansine versus capecitabine plus lapatinib in patients with previously treated HER2-positive advanced breast cancer (EMILIA): a descriptive analysis …

…, D Miles, S Verma, M Pegram, M Welslau… - The Lancet …, 2017 - thelancet.com
Background The antibody–drug conjugate trastuzumab emtansine is indicated for the
treatment of patients with HER2-positive metastatic breast cancer previously treated with …

[HTML][HTML] Trastuzumab emtansine (T-DM1) versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer and central nervous system …

…, J Huober, M Lu, D Miles, M Samant, M Welslau… - Annals of …, 2015 - Elsevier
Background We characterized the incidence of central nervous system (CNS) metastases
after treatment with trastuzumab emtansine (T-DM1) versus capecitabine–lapatinib (XL), and …

A review of the infection pathogenesis and prophylaxis recommendations in patients with chronic lymphocytic leukemia

T Tadmor, M Welslau, I Hus - Expert Review of Hematology, 2018 - Taylor & Francis
Introduction: The majority of patients with CLL will suffer from infections during their disease,
accounting for approximately 60% of deaths in CLL. Patients are predisposed to infection …

Bendamustine plus rituximab versus fludarabine plus rituximab for patients with relapsed indolent and mantle-cell lymphomas: a multicentre, randomised, open-label …

…, C Balser, M Stauch, W Brugger, M Welslau… - The Lancet …, 2016 - thelancet.com
Background Fludarabine-based chemoimmunotherapy with rituximab is frequently used in
patients with indolent and mantle-cell lymphomas who relapse after alkylating …

Patient‐reported outcomes from EMILIA, a randomized phase 3 study of trastuzumab emtansine (T‐DM1) versus capecitabine and lapatinib in human epidermal …

M Welslau, V Diéras, JH Sohn, SA Hurvitz, D Lalla… - Cancer, 2014 - Wiley Online Library
BACKGROUND This report describes the results of an analysis of patient‐reported
outcomes from EMILIA (TDM4370g/BO21977), a randomized phase 3 study of the antibody …

[HTML][HTML] Bendamustine plus rituximab is superior in respect of progression free survival and CR rate when compared to CHOP plus rituximab as first-line treatment of …

…, U von Gruenhagen, C Losem, G Heil, M Welslau… - Blood, 2009 - Elsevier
Abstract Abstract 405 Introduction: Promising results have been observed in two phase-II
studies evaluating the combination of Bendamustine plus Rituximab (BR) in patients with …

Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas

…, F Acker, S Fuhrmann, C Leng, M Welslau… - Blood …, 2021 - ashpublications.org
The antibody-drug conjugate polatuzumab vedotin (pola) has recently been approved in
combination with bendamustine and rituximab (pola-BR) for patients with refractory or …