[HTML][HTML] Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from …

…, CM Kelly, C Peña-Murillo, M Yilmaz, M Donica… - Annals of …, 2020 - Elsevier
Background Patients with brain metastases (BM) from human epidermal growth factor
receptor 2 (HER2)-positive breast cancer represent a difficult-to-treat population …

LBA15 Primary results from IMpassion131, a double-blind placebo-controlled randomised phase III trial of first-line paclitaxel (PAC)±atezolizumab (atezo) for …

…, M Patre, L Morales, K Russell, M Donica… - Annals of …, 2020 - annalsofoncology.org
Background In the phase 3 IMpassion130 trial, combining atezo with first-line nab-paclitaxel
for mTNBC showed significantly improved progression-free survival (PFS) and clinically …

Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage

MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2014 - Wiley Online Library
Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …

[HTML][HTML] Safety of trastuzumab emtansine (T-DM1) in patients with HER2-positive advanced breast cancer: primary results from the KAMILLA study cohort 1

…, N Quenel-Tueux, SC Linn, N Irahara, M Donica… - European journal of …, 2019 - Elsevier
Background Many patients with metastatic human epidermal growth factor receptor 2
(HER2)-positive breast cancer (BC) are candidates for trastuzumab emtansine (T-DM1) …

Phase II study (KAMELEON) of single‐agent T‐DM1 in patients with HER2‐positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma

…, D Castellano, G Erb, J Naab, M Donica… - Cancer …, 2023 - Wiley Online Library
The antibody‐drug conjugate trastuzumab emtansine (T‐DM1) is approved for human
epidermal growth factor receptor 2 (HER2/ERBB2)–positive breast cancer. We aimed to …

Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic subchondral bone and similarity to overlying cartilage

MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2016 - Wiley Online Library
Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …

Can the blood urea nitrogen/creatinine ratio distinguish upper from lower gastrointestinal bleeding?

RJ Richards, MB Donica, D Grayer - Journal of clinical …, 1990 - journals.lww.com
We wanted to know if the blood urea nitrogen to creatinine (BUN/Cr) ratio could help
distinguish upper from lower gastrointestinal bleeding. We analyzed retrospectively patients …

Primary results from CECILIA, a global single-arm phase II study evaluating bevacizumab, carboplatin and paclitaxel for advanced cervical cancer

…, P Ruff, M Estevez-Diz, N Irahara, M Donica… - Gynecologic …, 2020 - Elsevier
Objective Adding bevacizumab to cisplatin–paclitaxel for advanced cervical cancer
significantly improves overall and progression-free survival. We evaluated bevacizumab …

[HTML][HTML] Prospective, single-arm, longitudinal study of biomarkers in real-world patients with severe asthma

…, GW Canonica, C Picado, M Donica… - The Journal of Allergy …, 2020 - Elsevier
Background ARIETTA was a prospective, single-arm, noninterventional, multicenter study in
patients with severe asthma. Objective To examine the predictive and prognostic abilities of …

Safety and Efficacy of Bevacizumab Plus Standard-of-Care Treatment Beyond Disease Progression in Patients With Advanced Non–Small Cell Lung Cancer: The …

…, N Thatcher, A Das-Gupta, M Truman, M Donica… - JAMA …, 2018 - jamanetwork.com
Importance Bevacizumab treatment beyond progression has been investigated in breast
and metastatic colorectal cancers. Avastin in All Lines Lung (AvaALL) is the first randomized …