User profiles for "author:L. Sobrevia"
Professor Luis SobreviaDivision of Obstetrics and Gynecology, Faculty of Medicine, Pontificia Universidad Católica … Verified email at uc.cl Cited by 9814 |
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
…, DL Yudilevich, L Sobrevia - Physiological reviews, 2003 - journals.physiology.org
While transport processes for amino acids and glucose have long been known to be
expressed in the luminal and abluminal membranes of the endothelium comprising the …
expressed in the luminal and abluminal membranes of the endothelium comprising the …
[HTML][HTML] Oxidative stress: Normal pregnancy versus preeclampsia
…, F Toledo, CM Vázquez, A Mate, L Sobrevia… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …
Extracellular vesicles in obesity and diabetes mellitus
…, B Sobrevia, F Toledo, L Sobrevia - Molecular aspects of …, 2018 - Elsevier
Cell-to-cell communication happens via diverse mechanisms including the synthesis,
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …
[HTML][HTML] A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration
…, M Kobayashi, K Scholz-Romero, L Sobrevia… - PloS one, 2014 - journals.plos.org
Studies completed to date provide persuasive evidence that placental cell-derived
exosomes play a significant role in intercellular communication pathways that potentially …
exosomes play a significant role in intercellular communication pathways that potentially …
[HTML][HTML] Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis
C Salomon, J Ryan, L Sobrevia, M Kobayashi… - PloS one, 2013 - journals.plos.org
Vasculogenesis and angiogenesis are critical processes in fetal circulation and placental
vasculature development. Placental mesenchymal stem cells (pMSC) are known to release …
vasculature development. Placental mesenchymal stem cells (pMSC) are known to release …
[HTML][HTML] Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes
Migration of extravillous trophoblasts (EVT) into decidua and myometrium is a critical
process in the conversion of maternal spiral arterioles and establishing placenta perfusion …
process in the conversion of maternal spiral arterioles and establishing placenta perfusion …
[HTML][HTML] Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy
Background/Aim Hypercaloric diet ingestion and sedentary lifestyle result in obesity.
Metabolic syndrome is a cluster of clinical features secondary to obesity, considered as a …
Metabolic syndrome is a cluster of clinical features secondary to obesity, considered as a …
[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia
…, C Abad, D Rojas, F Toledo, L Sobrevia - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia
L Sobrevia, GE Mann - Experimental Physiology: Translation …, 1997 - Wiley Online Library
1. Vasodilatation induced by adenosine is mediated through the activation of A2‐
purinoceptors in endothelial and smooth muscle cells. 2. Adenosine induces a rapid and …
purinoceptors in endothelial and smooth muscle cells. 2. Adenosine induces a rapid and …
Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes
L Sobrevia, F Abarzúa, JK Nien, C Salomón… - Placenta, 2011 - Elsevier
Human endothelial dysfunction is a common feature in many diseases of pregnancy, such
as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide …
as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide …