User profiles for "author:L Kester"

Liesbeth Kester

- Verified email at uu.nl - Cited by 9630

Lennart Kester

- Verified email at prinsesmaximacentrum.nl - Cited by 7066

[HTML][HTML] Effects of flipping the classroom on learning outcomes and satisfaction: A meta-analysis

…, C Phielix, J Janssen, L Kester - Educational Research …, 2019 - Elsevier
In a flipped classroom, students study instructional material before class and apply this
material during class. To provide a statistical synthesis of current research on effects of …

[PDF][PDF] Single-cell transcriptomics meets lineage tracing

L Kester, A Van Oudenaarden - Cell stem cell, 2018 - cell.com
Reconstructing lineage relationships between cells within a tissue or organism is a long-
standing aim in biology. Traditionally, lineage tracing has been achieved through the …

[HTML][HTML] Self-regulated learning partially mediates the effect of self-regulated learning interventions on achievement in higher education: A meta-analysis

…, A Van Leeuwen, J Janssen, S Jak, L Kester - Educational Research …, 2019 - Elsevier
It is often assumed that interventions aimed at supporting students' self-regulated learning
(SRL) are effective for improving achievement because these interventions support SRL …

[HTML][HTML] Prospective derivation of a living organoid biobank of colorectal cancer patients

…, W van Houdt, J van Gorp, A Taylor-Weiner, L Kester… - Cell, 2015 - cell.com
In Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding
epithelial organoids that retain their tissue identity. We report the establishment of tumor …

Taking the load off a learner's mind: Instructional design for complex learning

…, PA Kirschner, L Kester - Educational …, 2003 - Taylor & Francis
Complex learning aims at the integration of knowledge, skills, and attitudes; the coordination
of qualitatively different constituent skills; and the transfer of what is learned to daily life or …

Single-cell messenger RNA sequencing reveals rare intestinal cell types

D Grün, A Lyubimova, L Kester, K Wiebrands, O Basak… - Nature, 2015 - nature.com
Understanding the development and function of an organ requires the characterization of all
of its cell types. Traditional methods for visualizing and isolating subpopulations of cells are …

An organoid platform for ovarian cancer captures intra-and interpatient heterogeneity

…, K Lõhmussaar, JE Valle-Inclan, N Hami, L Kester… - Nature medicine, 2019 - nature.com
Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage.
Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of …

Validation of noise models for single-cell transcriptomics

D Grün, L Kester, A Van Oudenaarden - Nature methods, 2014 - nature.com
Single-cell transcriptomics has recently emerged as a powerful technology to explore gene
expression heterogeneity among single cells. Here we identify two major sources of …

Integrated genome and transcriptome sequencing of the same cell

SS Dey, L Kester, B Spanjaard, M Bienko… - Nature …, 2015 - nature.com
Single-cell genomics and single-cell transcriptomics have emerged as powerful tools to
study the biology of single cells at a genome-wide scale. However, a major challenge is to …

Teaching complex rather than simple tasks: Balancing intrinsic and germane load to enhance transfer of learning

JJG Van Merriënboer, L Kester… - … Psychology: The Official …, 2006 - Wiley Online Library
Research indicates that effective instructional methods for practicing simple tasks differ from
effective methods for complex tasks. But unfortunately, load‐reducing methods that work …