Early detection of ovarian cancer

KM Elias, J Guo, RC Bast - Hematology/Oncology Clinics, 2018 - hemonc.theclinics.com
The rationale for early detection of ovarian cancer is compelling. Ovarian cancer confined to
the ovaries (stage I) can be cured in up to 90% of patients, and disease confined to the …

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

JD Milner, JM Brenchley, A Laurence, AF Freeman… - Nature, 2008 - nature.com
The autosomal dominant hyper-IgE syndrome (HIES,'Job's syndrome') is characterized by
recurrent and often severe pulmonary infections, pneumatoceles, eczema, staphylococcal …

[HTML][HTML] Educating healthcare providers to increase Human Papillomavirus (HPV) vaccination rates: A Qualitative Systematic Review

SOA Leung, B Akinwunmi, KM Elias, S Feldman - Vaccine: X, 2019 - Elsevier
Objectives HPV vaccination rates in the United States lag behind other developed countries.
Educational interventions are primarily directed at patients and parents rather than …

Multiple pregnancies with complete mole and coexisting normal fetus in North and South America: A retrospective multicenter cohort and literature review

LH Lin, I Maestá, A Braga, SY Sun, K Fushida… - Gynecologic …, 2017 - Elsevier
Objective To determine the clinical characteristics of multiple gestation with complete mole
and coexisting fetus (CHMCF) in North and South America. Methods Retrospective non …

[HTML][HTML] IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

L Wei, A Laurence, KM Elias, JJ O'Shea - Journal of biological chemistry, 2007 - ASBMB
CD4+ helper T cells can differentiate into several possible fates including: Th1, Th2, T
regulatory, and Th17 cells. Although, cytokine production by non-T cells is an important …

Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

KM Elias, A Laurence, TS Davidson… - Blood, The Journal …, 2008 - ashpublications.org
Abstract CD4+ helper T (Th) cells play a crucial role in the delicate balance between host
defense and autoimmune disease. Two important populations of helper T cells are the …

The Reporting on ERAS Compliance, Outcomes, and Elements Research (RECOvER) Checklist: A Joint Statement by the ERAS® and ERAS® USA Societies

KM Elias, AB Stone, K McGinigle… - World journal of …, 2019 - Wiley Online Library
Background Enhanced recovery after surgery (ERAS) programs are multimodal care
pathways designed to minimize the physiological and psychological impact of surgery for …

[HTML][HTML] Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

RA Davidowitz, LM Selfors, MP Iwanicki… - The Journal of …, 2014 - Am Soc Clin Investig
Metastatic dissemination of ovarian tumors involves the invasion of tumor cell clusters into
the mesothelial cell lining of peritoneal cavity organs; however, the tumor-specific factors …

[PDF][PDF] Platinum and PARP inhibitor resistance due to overexpression of microRNA-622 in BRCA1-mutant ovarian cancer

YE Choi, K Meghani, ME Brault, L Leclerc, YJ He… - Cell reports, 2016 - cell.com
High-grade serous ovarian carcinomas (HGSOCs) with BRCA1/2 mutations exhibit
improved outcome and sensitivity to double-strand DNA break (DSB)-inducing agents (ie …

Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer

KM Elias, W Fendler, K Stawiski, SJ Fiascone… - Elife, 2017 - elifesciences.org
Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC).
Combining small RNA sequencing from 179 human serum samples with a neural network …