Therapeutic strategy targeting the mTOR–HIF‐1α–VEGF pathway in ovarian clear cell adenocarcinoma

M Miyazawa, M Yasuda, M Fujita… - Pathology …, 2009 - Wiley Online Library
Malignant tumors usually involve a relatively hypoxic state, which induces overexpression of
hypoxia‐inducible factor‐1α (HIF‐1α) to satisfactorily enable the tumor to survive. Thus …

Establishment and characterization of a human malignant choroids plexus papilloma cell line (HIBCPP)

I Ishiwata, C ISHIWAT, E Ishiwata, Y SAT0… - Human …, 2005 - Wiley Online Library
A cell line designated “HIBSPP” was established from a human malignant choroids plexus
papilloma of 29‐year‐old Japanese woman. This line grew well without interruption for 3 …

[HTML][HTML] Proteomic analysis of differential protein expression by brain metastases of gynecological malignancies

A Yoshida, N Okamoto, A Tozawa-Ono, H Koizumi… - Human cell, 2013 - Springer
Brain metastases of gynecological malignancies are rare, but the incidence is increasing.
Patients with brain metastases have a poor prognosis, therefore early detection and optimal …

Side population is increased in paclitaxel-resistant ovarian cancer cell lines regardless of resistance to cisplatin

Y Kobayashi, K Seino, S Hosonuma, T Ohara… - Gynecologic …, 2011 - Elsevier
OBJECTIVES: In recent years, cancer stem cells (CSCs) have been reported to be
correlated with chemoresistance and may also be enriched in side populations (SPs). In this …

Psychological characteristics of Japanese gynecologic cancer patients after learning the diagnosis according to the hospital anxiety and depression scale

N Suzuki, M Ninomiya, S Maruta… - Journal of Obstetrics …, 2011 - Wiley Online Library
Aim: Anxiety and depression are common in cancer patients, because diagnosis of cancer
raises the fear of death. Although mental problems are often overlooked in cancer patients, it …

Alterations in the glycolipid composition and cellular properties of ovarian carcinoma‐derived RMG‐1 cells on transfection of the α1, 2‐fucosyltransferase gene

M Iwamori, K Tanaka, K Kubushiro, B Lin… - Cancer …, 2005 - Wiley Online Library
Transfection of the mouse Fut1 and Fut2, and human FUT1 genes into human ovarian
carcinoma‐derived RMG‐1 cells resulted in 20–30‐fold increases in cellular α1, 2 …

A patient-like orthotopic implantation nude mouse model of highly metastatic human ovarian cancer

K Kiguchi, T Kubota, D Aoki, Y Udagawa… - Clinical & experimental …, 1998 - Springer
Clinically relevant animal models of human cancer are important for studies of cancer
biology, invasion and metastasis, and for investigating new forms of prognostic diagnosis …

[HTML][HTML] Risk factors for perioperative venous thromboembolism: A retrospective study in Japanese women with gynecologic diseases

N Suzuki, N Yoshioka, T Ohara, N Yokomichi, T Nako… - Thrombosis …, 2010 - Springer
Background Patients with gynecologic cancer have a high risk of venous thromboembolism
(VTE) like patients with other cancers. However, there is little information on risk factors for …

Melatonin binding sites in estrogen receptor‐positive cells derived from human endometrial cancer

Y Kobayashi, MT Itoh, H Kondo, Y Okuma… - Journal of pineal …, 2003 - Wiley Online Library
Our previous work showed that melatonin (N‐acetyl‐5‐methoxytryptamine) inhibits
proliferation of the human endometrial cancer cell line, Ishikawa, which is estrogen receptor …

Novel glycobiomarker for ovarian cancer that detects clear cell carcinoma

M Sogabe, H Nozaki, N Tanaka, T Kubota… - Journal of Proteome …, 2014 - ACS Publications
Epithelial ovarian cancer (EOC) is often asymptomatic and thus diagnosed at advanced
stages with a poor prognosis. False-negative results for the conventional marker CA125 …