Vulvar cancer is a relatively rare gynecologic malignancy with an annual incidence in
developed countries of approximately 2 per 100,000 women. Vulvar squamous cell …

PURPOSE: To investigate the safety and clinical utility of the sentinel node procedure in
early-stage vulvar cancer patients. PATIENTS AND METHODS: A multicenter observational …

Near-infrared (NIR) fluorescence imaging has emerged as a promising complimentary
technique for intraoperative visualization of tumor tissue, lymph nodes and vital structures. In …

Abstract Recurrent disease occurs in 12–37% of patients with vulvar squamous cell
carcinoma (VSCC). Decisions about treatment of recurrent VSCC mainly depend on the …

Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage.
Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of …

Background Currently, all patients with vulvar cancer with a positive sentinel node undergo
inguinofemoral lymphadenectomy, irrespective of the size of sentinel-node metastases. Our …

Objective To present an update of the European Group on Tumor Markers guidelines for
serum markers in epithelial ovarian cancer. Methods Systematic literature survey from 2008 …

PURPOSE: Recommendations for women at high risk of ovarian cancer include periodic
gynecologic screening (GS) and prophylactic bilateral salpingo-oophorectomy (PBSO). The …

Abstract Programmed death-ligand 1 (PD-L1) is expressed in various immune cells and
tumor cells, and is able to bind to PD-1 on T lymphocytes, thereby inhibiting their function. At …

Purpose: Completeness of cytoreductive surgery is a key prognostic factor for survival in
patients with ovarian cancer. The ability to differentiate clearly between malignant and …