The Fos family of transcription factors and their role in tumourigenesis
K Milde-Langosch - European journal of cancer, 2005 - Elsevier
Members of the Fos family (c-Fos, FosB and its smaller splice variants, Fra-1 and Fra-2)
dimerise with Jun proteins to form the AP-1 transcription factor complex. Based on the …
dimerise with Jun proteins to form the AP-1 transcription factor complex. Based on the …
Role of protein glycosylation in cancer metastasis
L Oliveira-Ferrer, K Legler, K Milde-Langosch - Seminars in cancer biology, 2017 - Elsevier
Although altered glycosylation has been detected in human cancer cells decades ago, only
investigations in the last years have enormously increased our knowledge about the details …
investigations in the last years have enormously increased our knowledge about the details …
Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications
K Milde-Langosch, S Riethdorf, T Löning - Virchows Archiv, 2000 - Springer
Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In
this review, epidemiological and molecular data are combined to present a model for HPV …
this review, epidemiological and molecular data are combined to present a model for HPV …
[HTML][HTML] Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
C Eichelser, I Stückrath, V Müller, K Milde-Langosch… - Oncotarget, 2014 - ncbi.nlm.nih.gov
In this study, we compared the blood serum levels of circulating cell-free and exosomal
microRNAs, and their involvement in the molecular subtypes of breast cancer patients. Our …
microRNAs, and their involvement in the molecular subtypes of breast cancer patients. Our …
[HTML][HTML] Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer
X Meng, V Müller, K Milde-Langosch, F Trillsch… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Exosomes are membrane vesicles that mediate intercellular communication by transporting
their molecular cargo from cell to cell. We investigated whether serum levels of exosomal …
their molecular cargo from cell to cell. We investigated whether serum levels of exosomal …
[HTML][HTML] Clinical significance of p53 alterations in surgically treated prostate cancers
T Schlomm, L Iwers, P Kirstein, B Jessen, J Köllermann… - Modern pathology, 2008 - Elsevier
Despite the high number of previous studies, the role of p53 alterations in prostate cancer is
not clearly defined. To address the role of p53 alterations in prostate cancer biology, a total …
not clearly defined. To address the role of p53 alterations in prostate cancer biology, a total …
Overexpression of the p16 cell cycle inhibitor in breast cancer is associated with a more malignant phenotype
K Milde-Langosch, AM Bamberger, G Rieck… - Breast cancer research …, 2001 - Springer
In order to study the role of the p16 INK4A (MTS1/CDKN2a) tumor suppressor in breast
cancer, we analyzed p16 protein expression in 60 breast cancer samples which were also …
cancer, we analyzed p16 protein expression in 60 breast cancer samples which were also …
Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients
H Schwarzenbach, K Milde-Langosch… - Breast cancer research …, 2012 - Springer
MicroRNAs play a role in breast cancer development and progression by post-
transcriptional repression of the expression of important genes, such as the tumor …
transcriptional repression of the expression of important genes, such as the tumor …
[HTML][HTML] Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
Background: Owing to late diagnosis in advanced disease stages, prognosis of patients with
epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of …
epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of …
The role of the AP-1 transcription factors c-Fos, FosB, Fra-1 and Fra-2 in the invasion process of mammary carcinomas
K Milde-Langosch, H Röder, B Andritzky… - Breast cancer research …, 2004 - Springer
Members of the Fos family of AP-1 transcription factors (c-Fos, FosB, FosB2, Fra-1 and Fra-
2) are able to form dimers with Jun proteins which bind to the regulatory sequences of target …
2) are able to form dimers with Jun proteins which bind to the regulatory sequences of target …