[HTML][HTML] The IPBES Conceptual Framework—connecting nature and people
…, M Schultz, P Smith, R Sumaila, K Takeuchi… - Current opinion in …, 2015 - Elsevier
Highlights•We describe the IPBES Conceptual Framework.•It is a simplified model of
interactions between nature and people most relevant to IPBES's focus on sustainability.•It …
interactions between nature and people most relevant to IPBES's focus on sustainability.•It …
The Tropical Ocean‐Global Atmosphere observing system: A decade of progress
…, RW Reynolds, N Smith, K Takeuchi - Journal of …, 1998 - Wiley Online Library
A major accomplishment of the recently completed Tropical Ocean‐Global Atmosphere
(TOGA) Program was the development of an ocean observing system to support seasonal …
(TOGA) Program was the development of an ocean observing system to support seasonal …
Gastric mucosal defense and cytoprotection: bench to bedside
L Laine, K Takeuchi, A Tarnawski - Gastroenterology, 2008 - Elsevier
The gastric mucosa maintains structural integrity and function despite continuous exposure
to noxious factors, including 0.1 mol/L HCl and pepsin, that are capable of digesting tissue …
to noxious factors, including 0.1 mol/L HCl and pepsin, that are capable of digesting tissue …
Complete sequencing and characterization of 21,243 full-length human cDNAs
…, Y Nomura, S Togiya, F Komai, R Hara, K Takeuchi… - Nature …, 2004 - nature.com
As a base for human transcriptome and functional genomics, we created the “full-length long
Japan”(FLJ) collection of sequenced human cDNAs. We determined the entire sequence of …
Japan”(FLJ) collection of sequenced human cDNAs. We determined the entire sequence of …
Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro …
…, LY Bai, SY Oh, Y Choda, H Yasui, K Takeuchi… - The Lancet …, 2022 - thelancet.com
Background The additive or synergistic sustained antitumour effect of immune checkpoint
inhibitors in combination with oxaliplatin-based chemotherapy has previously been …
inhibitors in combination with oxaliplatin-based chemotherapy has previously been …
RET, ROS1 and ALK fusions in lung cancer
K Takeuchi, M Soda, Y Togashi, R Suzuki, S Sakata… - Nature medicine, 2012 - nature.com
Through an integrated molecular-and histopathology-based screening system, we
performed a screening for fusions of anaplastic lymphoma kinase (ALK) and c-ros oncogene …
performed a screening for fusions of anaplastic lymphoma kinase (ALK) and c-ros oncogene …
[HTML][HTML] Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts
T Nakamura, Y Imai, T Matsumoto, S Sato, K Takeuchi… - Cell, 2007 - cell.com
Estrogen prevents osteoporotic bone loss by attenuating bone resorption; however, the
molecular basis for this is unknown. Here, we report a critical role for the osteoclastic …
molecular basis for this is unknown. Here, we report a critical role for the osteoclastic …
Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
…, T Takano, Y Tsukamoto, M Yoshiyama, K Takeuchi… - Circulation, 2001 - Am Heart Assoc
Background—There is accumulating data that acute coronary syndromes relate to recent
onset activation of inflammation affecting atherosclerotic plaques. Increased blood levels of …
onset activation of inflammation affecting atherosclerotic plaques. Increased blood levels of …
Integrated molecular analysis of adult T cell leukemia/lymphoma
…, Y Miyazaki, A Takaori-Kondo, F Matsuda, K Takeuchi… - Nature …, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …
KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
K Takeuchi, YL Choi, Y Togashi, M Soda, S Hatano… - Clinical Cancer …, 2009 - AACR
Purpose: EML4-ALK is a transforming fusion tyrosine kinase, several isoforms of which have
been identified in lung cancer. Immunohistochemical detection of EML4-ALK has proved …
been identified in lung cancer. Immunohistochemical detection of EML4-ALK has proved …