Management of borderline ovarian neoplasms

I Cadron, K Leunen, T Van Gorp, F Amant… - Journal of clinical …, 2007 - ascopubs.org
Over the last decades, the management of borderline ovarian tumors (BOTs) has changed
from radical surgery to more conservative therapy as a result of the need for fertility-sparing …

Timing of debulking surgery in advanced ovarian cancer

I Vergote, T Van Gorp, F Amant, K Leunen… - International Journal of …, 2008 - ijgc.bmj.com
It is clear that primary debulking remains the standard of care within the treatment of
advanced ovarian cancer (FIGO stage III and IV). This debulking surgery should be …

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

…, DO Stram, P Neven, AS Dieudonné, K Leunen… - Nature …, 2013 - nature.com
Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a
higher proportion occurring in younger women and women of African ancestry. The etiology …

Genome-wide association analysis identifies three new breast cancer susceptibility loci

…, D Lambrechts, BT Yesilyurt, G Floris, K Leunen… - Nature …, 2012 - nature.com
Breast cancer is the most common cancer among women. To date, 22 common breast
cancer susceptibility loci have been identified accounting for∼ 8% of the heritability of the …

[HTML][HTML] HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm

…, I Cadron, E Despierre, A Daemen, K Leunen… - British journal of …, 2011 - nature.com
Background: Recently, a Risk of Ovarian Malignancy Algorithm (ROMA) utilising human
epididymis secretory protein 4 (HE4) and CA125 successfully classified patients as …

Whole-body MRI with diffusion-weighted sequence for staging of patients with suspected ovarian cancer: a clinical feasibility study in comparison to CT and FDG-PET …

…, I Vergote, K Op de beeck, F Amant, K Leunen… - European …, 2014 - Springer
Objectives To evaluate whole-body MRI with diffusion-weighted sequence (WB-DWI/MRI) for
staging and assessing operability compared with CT and FDG-PET/CT in patients with …

[HTML][HTML] CHEK2* 1100delC heterozygosity in women with breast cancer associated with early death, breast cancer–specific death, and increased risk of a second …

…, C Seynaeve, AB Ekici, K Leunen… - Journal of clinical …, 2012 - ncbi.nlm.nih.gov
CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early
Death, Breast Cancer–Specific Death, and Increased Risk of a Second Breast Cancer …

[HTML][HTML] Clinical study investigating the role of lymphadenectomy, surgical castration and adjuvant hormonal treatment in endometrial stromal sarcoma

F Amant, A De Knijf, B Van Calster, K Leunen… - British journal of …, 2007 - nature.com
The objective of this study is to assess the therapeutic importance of surgical castration,
adjuvant hormonal treatment and lymphadenectomy in endometrial stromal sarcoma (ESS) …

Effect of manual lymph drainage in addition to guidelines and exercise therapy on arm lymphoedema related to breast cancer: randomised controlled trial

…, I Geraerts, S Truijen, A Smeets, K Leunen… - Bmj, 2011 - bmj.com
Objective To determine the preventive effect of manual lymph drainage on the development
of lymphoedema related to breast cancer. Design Randomised single blinded controlled …

Neoadjuvant chemotherapy in advanced ovarian cancer: on what do we agree and disagree?

…, F Amant, F Heitz, K Leunen… - Gynecologic …, 2013 - gynecologiconcology-online.net
Following the recent publication of the randomized study in stages IIIC and IV ovarian
cancer of the European Organisation for Treatment and Research—Gynaecological Cancer …