Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …

Publisher Summary This chapter presents the procedure for preparation of high molecular
weight RNA. High molecular weight RNA can be isolated from haploid or diploid yeast cells …

In the yeast Saccharomyces cerevisiae, vacuolar proteins such as carboxypeptidase Y
transit from the Golgi to the lysosome-like vacuole via an endosome-like intermediate …

Despite development of new antiviral drugs, viral infections are still a major health problem.
The most potent antiviral defense mechanism is the innate production of type I interferon …

Intrahepatic cholestasis of pregnancy (ICP) represents the most common pregnancy-related
liver disease in women. Women frequently present in the third trimester with pruritus and …

The polymerase chain reaction (PCR) was used to study the prevalence of the macrolide
resistance genes ermA, ermB, ermC, msrA/msrB, ereA and ereB, in 851 clinical isolates of …

Current classification of gliomas is based on histological criteria according to the World
Health Organization (WHO) classification of tumors of the central nervous system. Over the …

The purpose of this study was the appraisal of the clinical and functional consequences of
germline mutations within the gene for the IL-2 inducible T-cell kinase, ITK. Among patients …

One hundred sixteen unrelated clinical isolates of Staphylococcus aureus (70 ciprofloxacin
resistant and 46 ciprofloxacin susceptible) from eight countries were studied for the …

Mammalian sirtuins are involved in the control of metabolism and life-span regulation. Here,
we link the mitochondrial sirtuin SIRT4 with cellular senescence, skin aging, and …