Work performed with differentiated contractile smooth muscle tissue over the last two
decades has made clear that covalent modification of myosin by phosphorylation of the 20 …

The smooth muscle cell directly drives the contraction of the vascular wall and hence
regulates the size of the blood vessel lumen. We review here the current understanding of …

This minireview will cover current concepts on the identity and mechanistic function of
smooth muscle actin binding proteins that may regulate actin-myosin interactions. The …

Material moduli of the cytoskeleton (CSK) influence a wide range of cell functions,,. There is
substantial evidence from reconstituted F-actin gels that a regime exists in which the moduli …

• Introduction• Mechanisms that regulate LC20 phosphorylation‐Regulation of myosin
phosphatase‐CaMKII• Mechanisms that regulate the access of myosin to actin‐Caldesmon …

1. Intracellular recordings were obtained from circular smooth muscle fibres of the canine
fundus, corpus, antrum and pylorus as well as from the human corpus and antrum. 2. In the …

Dynamic remodeling of the actin cytoskeleton plays an essential role in the migration and
proliferation of vascular smooth muscle cells. It has been suggested that actin remodeling …

This review focuses on the vascular smooth muscle cells present in the medial layer of the
blood vessels wall in the fully differentiated state (dVSMCs). The dVSMC contractile …

The purpose of this study was to investigate the potential role of mitogen-activated protein
(MAP) kinase in smooth muscle contraction by monitoring MAP kinase activation, caldesmon …

An interaction between extracellular regulated kinase 1 (ERK1) and calponin has previously
been reported (Menice, Hulvershorn, Adam, Wang and Morgan (1997) J. Biol. Chem. 272 …