High-grade serous carcinoma (HGSC) is the most common and lethal subtype of ovarian
cancer. Research over the past decade has strongly suggested that “ovarian” HGSC arises …

Background: A randomized trial conducted by the Gynecologic Oncology Group (GOG,
study# 111) in the United States showed a better outcome for patients with advanced …

Background Granulosa-cell tumors (GCTs) are the most common type of malignant ovarian
sex cord–stromal tumor (SCST). The pathogenesis of these tumors is unknown. Moreover …

PURPOSE Taxol (paclitaxel; Bristol-Myers Squibb, Wallingford, CT) is a new anticancer
agent with activity in a number of human tumors, including epithelial ovarian cancer. In …

Although there are recognized differences in the type of ovarian carcinomas between those
tumors diagnosed at low versus high stage, there is a lack of data on stage distribution of …

Objective The purpose of this study was to assess the uptake and perioperative safety of
bilateral salpingectomy (BS) as an ovarian cancer risk-reduction strategy in low-risk women …

PURPOSE: To evaluate the efficacy of carboplatin plus paclitaxel in primarily advanced or
recurrent endometrial cancers. PATIENTS AND METHODS: Four distinct patient groups …

Six hundred nineteen patients with metastatic breast cancer, treated with a combination of 5-
fluorouracil, Adriamycin, and cyclophosphamide, or close variations of this program, with or …

Background The response rate of ovarian mucinous carcinomas to paclitaxel/carboplatin is
low, prompting interest in targeted molecular therapies. We investigated HER2 expression …

Purpose: To determine the efficacy and toxicity of a combined-modality regimen of
irradiation with platinum-based combination chemotherapy in small-cell carcinoma of the …