Objective To investigate pregnancy outcomes in women after abdominal radical
trachelectomy (RT) for early-stage cervical cancer. Methods The patients' background …

STUDY QUESTION What are the reproductive and obstetric outcomes in patients
undergoing radical abdominal trachelectomy (RAT) for early-stage cervical cancer …

Lymph node metastasis is the major clinicopathologic feature associated with poor
prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Here, web …

Background Immune responses in the uterine cervix are considered to play an important
role in persistent human papillomavirus (HPV) infection and carcinogenesis, but many …

Background: Fertility preservation is important for women of reproductive age with cervical
cancer. The underlying reasons behind suboptimal reproductive results after successful …

Background Prognostic clinicopathological factors for type 1 endometrial cancer are
unknown and the purpose of the current study was to determine the independent prognostic …

The PD-1/PD-L1 blockade is now recognized as one of the basic immune interventions for
development of combination cancer immunotherapy. We have been screening chemical …

Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been widely used. They
inhibit proximal tubular glucose reabsorption, resulting in glycosuria. Herein, we report the …

Cancer immunotherapies, particularly immune-checkpoint blockade and T cell-based
adoptive cell therapy, have recently been recognized as cancer treatments that show strong …

Although cancer immunotherapy has recently demonstrated durable responses even in
patients with advanced cancer, not all patients or cancer types respond to the therapy …