New findings on extinction of conditioned fear early in development: theoretical and clinical implications
JH Kim, R Richardson - Biological psychiatry, 2010 - Elsevier
Research with adult animals suggests that extinction depends, at least partly, on new
inhibitory learning that is specific to the context in which it is learned. However, several …
inhibitory learning that is specific to the context in which it is learned. However, several …
Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label …
SB Kang, JW Park, SY Jeong, BH Nam, HS Choi… - The lancet …, 2010 - thelancet.com
Background The safety and short-term efficacy of laparoscopic surgery for rectal cancer after
preoperative chemoradiotherapy has not been demonstrated. The aim of the randomised …
preoperative chemoradiotherapy has not been demonstrated. The aim of the randomised …
[HTML][HTML] Trastuzumab deruxtecan versus trastuzumab emtansine for breast cancer
Background Trastuzumab emtansine is the current standard treatment for patients with
human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer whose …
human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer whose …
Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non …
Background Compared with open resection, laparoscopic resection of rectal cancers is
associated with improved short-term outcomes, but high-level evidence showing similar long …
associated with improved short-term outcomes, but high-level evidence showing similar long …
Role of cues and contexts on drug‐seeking behaviour
Environmental stimuli are powerful mediators of craving and relapse in substance‐abuse
disorders. This review examined how animal models have been used to investigate the …
disorders. This review examined how animal models have been used to investigate the …
Predictive and prognostic impact of epidermal growth factor receptor mutation in non–small-cell lung cancer patients treated with gefitinib
Purpose This study was undertaken to investigate the effects of epidermal growth factor
receptor (EGFR) mutation and its downstream signaling on response and survival in non …
receptor (EGFR) mutation and its downstream signaling on response and survival in non …
Developmental rodent models of fear and anxiety: from neurobiology to pharmacology
DE Ganella, JH Kim - British journal of pharmacology, 2014 - Wiley Online Library
Anxiety disorders pose one of the biggest threats to mental health in the world, and they
predominantly emerge early in life. However, research of anxiety disorders and fear‐related …
predominantly emerge early in life. However, research of anxiety disorders and fear‐related …
[HTML][HTML] Intratumoral heterogeneity of HER2 gene amplification in breast cancer: its clinicopathological significance
Intratumoral heterogeneity of human epidermal growth factor receptor 2 (HER2) gene
amplification has been reported to occur with variable frequencies in breast cancers …
amplification has been reported to occur with variable frequencies in breast cancers …
[HTML][HTML] High EGFR gene copy number predicts poor outcome in triple-negative breast cancer
HS Park, MH Jang, EJ Kim, HJ Kim, HJ Lee, YJ Kim… - Modern pathology, 2014 - Elsevier
Epidermal growth factor receptor (EGFR) is frequently overexpressed in triple-negative
breast cancer and is emerging as a therapeutic target. EGFR gene copy number alteration …
breast cancer and is emerging as a therapeutic target. EGFR gene copy number alteration …
Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double …
Background The oral AKT inhibitor ipatasertib is being investigated in cancers with a high
prevalence of PI3K/AKT pathway activation, including triple-negative breast cancer. The …
prevalence of PI3K/AKT pathway activation, including triple-negative breast cancer. The …